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Cited by 753

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Inhibition of Bacterial Adherence by Secretory Immunoglobulin A: A Mechanism of Antigen Disposal

Williams, R. C., Gibbons, R. J.·1972·Science

Abstract

Preparations of secretory immunoglobulin A (S-IgA) isolated from human parotid fluid specifically inhibited the adherence of Streptococcus strains to epithelial cells. Since bacterial adherence is a prerequisite for colonization of mucous surfaces. S-IgA-mediated inhibition of adherence would limit bacterial colonization. This mechanism can explain how secretory immunoglobulins function in the disposal of bacterial antigens.

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Crossref · 10.1126/science.177.4050.697

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Metadata

Authors
Williams, R. C., & Gibbons, R. J.
Venue
Science
Published
1972-08-25
Volume
177
Issue
4050
Pages
697-699
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2017646214
Cited by
753
References
0
FWCI
49.06
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Inhibition of Bacterial Adherence by Secretory Immunoglobulin A: A Mechanism of Antigen Disposal. https://app.cochat.ai/papers/10.1126/science.177.4050.697
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Williams, R. C., & Gibbons, R. J. (1972). Inhibition of Bacterial Adherence by Secretory Immunoglobulin A: A Mechanism of Antigen Disposal. Science. https://doi.org/10.1126/science.177.4050.697

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.