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Cited by 266

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Behavioral Maintenance of High Concentrations of Blood Ethanol and Physical Dependence in the Rat

Falk, John L., Samson, Herman H., Winger, Gail·1972·Science

Abstract

Rats maintained on an intermittent food schedule with an available ethanol solution drink to excess (13.1 grams of ethanol per kilogram of body weight, daily). Removal of ethanol produces symptoms of physical dependence including death from tonic-clonic seizures. Overindulgence in oral self-administration of an aqueous ethanol solution, resulting in unequivocal physical dependence, approximates a model of human alcoholism.

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Metadata

Authors
Falk, J. L., Samson, H. H., & Winger, G.
Venue
Science
Published
1972-09
Volume
177
Issue
4051
Pages
811-813
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2039705257
Cited by
266
References
0
FWCI
6.03
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Behavioral Maintenance of High Concentrations of Blood Ethanol and Physical Dependence in the Rat. https://app.cochat.ai/papers/10.1126/science.177.4051.811
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Falk, J. L., Samson, H. H., & Winger, G. (1972). Behavioral Maintenance of High Concentrations of Blood Ethanol and Physical Dependence in the Rat. Science. https://doi.org/10.1126/science.177.4051.811

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.