The DOI matches its Crossref record.
Detection of Heat-Labile Escherichia coli Enterotoxin with the Use of Adrenal Cells in Tissue Culture
Abstract
Cell-free culture filtrates of heat-labile enterotoxin-producing strains of Escherichia coli are capable of inducing morphological changes and steroidogenesis in monolayer cultures of adrenal cells. These tissue culture changes are similar to those induced by cholera enterotoxin and cannot be effected by culture filtrates of other enterotoxigenic or enteropathogenic types of bacteria. The results of the tissue culture studies correlated well with those done in the standard intestinal-loop systems and suggest that this tissue culture system could be used to significantly aid epidemiological and molecular studies with heat-labile Escherichia coli enterotoxin.
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Cited by
Karmali, M. A., Petric, M., Lim, C., Fleming, P. C., Arbus, G. S., & Lior, H. (1985) · Journal of Infectious Diseases · doi:10.1093/infdis/151.5.775 · Cited by 1,388
Evans, D. G., Evans, D. J., & Tjoa, W. (1977) · Infection and Immunity · doi:10.1128/iai.18.2.330-337.1977 · Cited by 527
Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion
Sears, C. L., & Kaper, J. B. (1996) · Microbiological Reviews · doi:10.1128/mmbr.60.1.167-215.1996 · Cited by 508
Metadata
- Authors
- Donta, S. T., Moon, H. W., & Whipp, S. C.
- Venue
- Science
- Published
- 1974-01-25
- Volume
- 183
- Issue
- 4122
- Pages
- 334-336
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2063124395
- Cited by
- 392
- References
- 0
- FWCI
- 28.10
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Detection of Heat-Labile Escherichia coli Enterotoxin with the Use of Adrenal Cells in Tissue Culture. https://app.cochat.ai/papers/10.1126/science.183.4122.334
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- Donta, S. T., Moon, H. W., & Whipp, S. C. (1974). Detection of Heat-Labile Escherichia coli Enterotoxin with the Use of Adrenal Cells in Tissue Culture. Science. https://doi.org/10.1126/science.183.4122.334
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
