The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Novel Fold and Putative Receptor Binding Site of Granulocyte-Macrophage Colony-Stimulating Factor
Open accessAbstract
Granulocyte-macrophage colony-stimulating factor (GM-CSF) stimulates the development of and the cytotoxic activity of white blood cells. Recombinant human GM-CSF has proven useful in the treatment of blood disorders. The structure of GM-CSF, which was determined at 2.4 angstrom resolution by x-ray crystallography, has a novel fold combining a two-stranded antiparallel β sheet with an open bundle of four α helices. Residues implicated in receptor recognition, which are distant in the primary sequence, are on adjacent α helices in the folded protein. A working model for the receptor binding site is presented.
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Kabsch, W., & Sander, C. (1983) · Biopolymers · doi:10.1002/bip.360221211 · Cited by 15,320
Karplus, P. A., Daniels, M. J., & Herriott, J. R. (1991) · Science · doi:10.1126/science.1986412 · Cited by 536
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Bennett, M. J., Choe, S., & Eisenberg, D. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.8.3127 · Cited by 532
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Louie, A. Y., & Meade, T. J. (1999) · Chemical Reviews · doi:10.1021/cr9804285 · Cited by 301
GOFFIN, V., SHIVERICK, K. T., KELLY, P. A., & MARTIAL, J. A. (1996) · Endocrine Reviews · doi:10.1210/edrv-17-4-385 · Cited by 293
Metadata
- Authors
- Diederichs, K., Boone, T., & Karplus, P. A.
- Venue
- Science
- Published
- 1991-12-20
- Volume
- 254
- Issue
- 5039
- Pages
- 1779-1782
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2067377498
- Cited by
- 202
- References
- 2
- FWCI
- 10.91
- Type
- journal article
- Language
- en
- Open access
- green
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- Diederichs, K., Boone, T., & Karplus, P. A. (1991). Novel Fold and Putative Receptor Binding Site of Granulocyte-Macrophage Colony-Stimulating Factor. Science. https://doi.org/10.1126/science.1837174
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
