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Cited by 584

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Chromosome Aberrations and Cancer

Solomon, Ellen, Borrow, Julian, Goddard, Audrey D.·1991·Science

Abstract

Cancer may be defined as a progressive series of genetic events that occur in a single clone of cells because of alterations in a limited number of specific genes: the oncogenes and tumor suppressor genes. The association of consistent chromosome aberrations with particular types of cancer has led to the identification of some of these genes and the elucidation of their mechanisms of action. Consistent chromosome aberrations are observed not only in rare tumor types but also in the relatively common lung, colon, and breast cancers. Identification of additional mutated genes through other chromosomal abnormalities will lead to a more complete molecular description of oncogenesis.

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Crossref · 10.1126/science.1957167

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Metadata

Authors
Solomon, E., Borrow, J., & Goddard, A. D.
Venue
Science
Published
1991-11-22
Volume
254
Issue
5035
Pages
1153-1160
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2051296872
Cited by
584
References
2
FWCI
32.46
Type
journal article
Language
en
Open access
closed

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