The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Monoclonal Antibodies in Diagnosis and Therapy
Abstract
Monoclonal antibodies have been applied clinically to the diagnosis and therapy of an array of human disorders, including cancer and infectious diseases, and have been used for the modulation of immune responses. Effective therapy using unmodified monoclonal antibodies has, however, been elusive. Recently, monoclonal antibody-mediated therapy has been revolutionized by advances such as the definition of cell-surface structures on abnormal cells as targets for effective monoclonal antibody action, genetic engineering to create less immunogenic and more effective monoclonal antibodies, and the arming of such antibodies with toxins or radionuclides to enhance their effector function.
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Citations
Cites
Replacing the complementarity-determining regions in a human antibody with those from a mouse
Jones, P. T., Dear, P. H., Foote, J., Neuberger, M. S., & Winter, G. (1986) · Nature · doi:10.1038/321522a0 · Cited by 1,406
Cited by
Metabolic flux distributions in Corynebacterium glutamicum during growth and lysine overproduction
Vallino, J. J., & Stephanopoulos, G. (1993) · Biotechnology and Bioengineering · doi:10.1002/bit.260410606 · Cited by 508
Radiometal-Labeled Agents (Non-Technetium) for Diagnostic Imaging
Anderson, C. J., & Welch, M. J. (1999) · Chemical Reviews · doi:10.1021/cr980451q · Cited by 455
Metadata
- Authors
- Waldmann, T. A.
- Venue
- Science
- Published
- 1991-06-21
- Volume
- 252
- Issue
- 5013
- Pages
- 1657-1662
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1970296191
- Cited by
- 385
- References
- 1
- FWCI
- 46.20
- Type
- journal article
- Language
- en
- Open access
- closed
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- Waldmann, T. A. (1991). Monoclonal Antibodies in Diagnosis and Therapy. Science. https://doi.org/10.1126/science.2047874
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
