The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Toward a Science of Metabolic Engineering
Abstract
Application of recombinant DNA methods to restructure metabolic networks can improve production of metabolite and protein products by altering pathway distributions and rates. Recruitment of heterologous proteins enables extension of existing pathways to obtain new chemical products, alter posttranslational protein processing, and degrade recalcitrant wastes. Although some of the experimental and mathematical tools required for rational metabolic engineering are available, complex cellular responses to genetic perturbations can complicate predictive design.
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Khosla, C., & Bailey, J. E. (1989) · Journal of Bacteriology · doi:10.1128/jb.171.11.5995-6004.1989 · Cited by 103
Self-citation
Cited by
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Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development
Paddon, C. J., & Keasling, J. D. (2014) · Nature Reviews Microbiology · doi:10.1038/nrmicro3240 · Cited by 675
Flux Distributions in Anaerobic, Glucose-Limited Continuous Cultures of Saccharomyces Cerevisiae
Nissen, T. L., Schulze, U., Nielsen, J., & Villadsen, J. (1997) · Microbiology · doi:10.1099/00221287-143-1-203 · Cited by 376
Poly(hydroxyalkanoates): A Fifth Class of Physiologically Important Organic Biopolymers?
Müller, H., & Seebach, D. (1993) · Angewandte Chemie International Edition in English · doi:10.1002/anie.199304771 · Cited by 363
Third Generation Biofuels via Direct Cellulose Fermentation
Carere, C. R., Sparling, R., Cicek, N., & Levin, D. B. (2008) · International Journal of Molecular Sciences · doi:10.3390/ijms9071342 · Cited by 339
Metadata
- Authors
- Bailey, J. E.
- Venue
- Science
- Published
- 1991-06-21
- Volume
- 252
- Issue
- 5013
- Pages
- 1668-1675
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2034645234
- Cited by
- 1,165
- References
- 1
- FWCI
- 7.23
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bailey, J. E. (1991). Toward a Science of Metabolic Engineering. Science. https://doi.org/10.1126/science.2047876
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
