The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
GABA A -Receptor Function in Hippocampal Cells Is Maintained by Phosphorylation Factors
Abstract
Gamma aminobutyric acid (GABA) mediates fast synaptic inhibition in the central nervous system by activating the chloride-permeable GABA A channel. The GABA A conductance progressively diminishes with time when the intracellular contents of hippocampal neurons are perfused with a minimal intracellular medium. This "run down" of the GABA-activated conductance can be prevented by the inclusion of magnesium adenosine triphosphate and calcium buffer in the intracellular medium. The amount of chloride conductance that can be activated by GABA is determined by competition between a calcium-dependent process that reduces the conductance and a phosphorylation process that maintains the conductance.
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Cites
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Tsien, R. Y. (1980) · Biochemistry · doi:10.1021/bi00552a018 · Cited by 2,236
Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family
Schofield, P. R., Darlison, M. G., Fujita, N., Burt, D. R., Stephenson, F. A., Rodriguez, H., Rhee, L. M., Ramachandran, J., Reale, V., Glencorse, T. A., et al. (1987) · Nature · doi:10.1038/328221a0 · Cited by 1,622
Benovic, J. L., Strasser, R. H., Caron, M. G., & Lefkowitz, R. J. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.9.2797 · Cited by 662
Dichter, M. A. (1978) · Brain Research · doi:10.1016/0006-8993(78)90476-6 · Cited by 480
Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization
Huganir, R. L., Delcour, A. H., Greengard, P., & Hess, G. P. (1986) · Nature · doi:10.1038/321774a0 · Cited by 418
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Isolation of neurons suitable for patch-clamping from adult mammalian central nervous systems
Kay, A. R., & Wong, R. K. S. (1986) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(86)90040-3 · Cited by 409
Self-citationAn enzymatic mechanism for calcium current inactivation in dialysed Helix neurones.
Chad, J. E., & Eckert, R. (1986) · The Journal of Physiology · doi:10.1113/jphysiol.1986.sp016206 · Cited by 406
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Cited by
Berridge, C. W., & Waterhouse, B. D. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(03)00143-7 · Cited by 2,529
Macdonald, R. L., & Olsen, R. W. (1994) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.17.030194.003033 · Cited by 1,975
Inhibition of GABAASynaptic Responses by Brain-Derived Neurotrophic Factor (BDNF) in Rat Hippocampus
Tanaka, T., Saito, H., & Matsuki, N. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-09-02959.1997 · Cited by 385
“GABA A receptor function is maintained by phosphorylation and disrupted by [Ca 2ϩ ] i elevation (Stelzer et al., 1988; Marchenko, 1991; Gyenes et al., 1994; Moss et al., 1995).”
BackgroundMulle, C., Choquet, D., Korn, H., & Changeux, J.-P. (1992) · Neuron · doi:10.1016/0896-6273(92)90115-t · Cited by 351
γ‐Aminobutyric acidA neurotransmission and cerebral ischemia
Schwartz‐Bloom, R. D., & Sah, R. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00274.x · Cited by 323
Metadata
- Authors
- Stelzer, A., Kay, A. R., & Wong, R. K. S.
- Venue
- Science
- Published
- 1988-07-15
- Volume
- 241
- Issue
- 4863
- Pages
- 339-341
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2010009395
- Cited by
- 301
- References
- 29
- FWCI
- 9.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: GABA A -Receptor Function in Hippocampal Cells Is Maintained by Phosphorylation Factors. https://app.cochat.ai/papers/10.1126/science.2455347
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- Stelzer, A., Kay, A. R., & Wong, R. K. S. (1988). GABA A -Receptor Function in Hippocampal Cells Is Maintained by Phosphorylation Factors. Science. https://doi.org/10.1126/science.2455347
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
