The DOI matches its Crossref record.
Nutritional Importance of Pyrroloquinoline Quinone
Abstract
Mice fed a chemically defined diet devoid of pyrroloquinoline quinone (PQQ) grew poorly, failed to reproduce, and became osteolathyritic. Moreover, severely affected mice had friable skin, skin collagen that was readily extractable into neutral salt solutions, and decreased lysyl oxidase. The identification of functional defects in connective tissue and the growth retardation associated with PQQ deprivation suggest that PQQ plays a fundamental role as a growth factor or vitamin.
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Metadata
- Authors
- Killgore, J., Smidt, C., Duich, L., Romero-Chapman, N., Tinker, D., Reiser, K., Melko, M., Hyde, D., & Rucker, R. B.
- Venue
- Science
- Published
- 1989-08-25
- Volume
- 245
- Issue
- 4920
- Pages
- 850-852
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2082651990
- Cited by
- 202
- References
- 0
- FWCI
- 3.84
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Nutritional Importance of Pyrroloquinoline Quinone. https://app.cochat.ai/papers/10.1126/science.2549636
- The paper
- Killgore, J., Smidt, C., Duich, L., Romero-Chapman, N., Tinker, D., Reiser, K., Melko, M., Hyde, D., & Rucker, R. B. (1989). Nutritional Importance of Pyrroloquinoline Quinone. Science. https://doi.org/10.1126/science.2549636
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
