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Cited by 399

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Polyhydroxybutyrate, a Biodegradable Thermoplastic, Produced in Transgenic Plants

Poirier, Yves, Dennis, Douglas E., Klomparens, Karen, Somerville, Chris·1992·Science

Abstract

Polyhydroxybutyrate (PHB), a high molecular weight polyester, is accumulated as a storage carbon in many species of bacteria and is a biodegradable thermoplastic. To produce PHB by genetic engineering in plants, genes from the bacterium Alcaligenes eutrophus that encoded the two enzymes required to convert acetoacetyl—coenzyme A to PHB were placed under transcriptional control of the cauliflower mosaic virus 35S promoter and introduced into Arabidopsis thaliana . Transgenic plant lines that contained both genes accumulated PHB as electron-lucent granules in the cytoplasm, nucleus, and vacuole; the size and appearance of these granules were similar to the PHB granules that accumulate in bacteria.

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Metadata

Authors
Poirier, Y., Dennis, D. E., Klomparens, K., & Somerville, C.
Venue
Science
Published
1992-04-24
Volume
256
Issue
5056
Pages
520-523
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2078182305
Cited by
399
References
0
FWCI
16.92
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Polyhydroxybutyrate, a Biodegradable Thermoplastic, Produced in Transgenic Plants. https://app.cochat.ai/papers/10.1126/science.256.5056.520
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Poirier, Y., Dennis, D. E., Klomparens, K., & Somerville, C. (1992). Polyhydroxybutyrate, a Biodegradable Thermoplastic, Produced in Transgenic Plants. Science. https://doi.org/10.1126/science.256.5056.520

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.