The DOI matches its Crossref record.
DNA Mismatch Correction in a Defined System
Abstract
DNA mismatch correction is a strand-specific process involving recognition of noncomplementary Watson-Crick nucleotide pairs and participation of widely separated DNA sites. The Escherichia coli methyl-directed reaction has been reconstituted in a purified system consisting of MutH, MutL, and MutS proteins, DNA helicase II, single-strand DNA binding protein, DNA polymerase III holoenzyme, exonuclease I, DNA ligase, along with ATP (adenosine triphosphate), and the four deoxynucleoside triphosphates. This set of proteins can process seven of the eight base-base mismatches in a strand-specific reaction that is directed by the state of methylation of a single d(GATC) sequence located 1 kilobase from the mispair.
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Cited by
Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase
Steinhauer, D. A., Domingo, E., & Holland, J. J. (1992) · Gene · doi:10.1016/0378-1119(92)90216-c · Cited by 415
DNA synthesis errors associated with double-strand-break repair.
Strathern, J. N., Shafer, B. K., & McGill, C. B. (1995) · Genetics · doi:10.1093/genetics/140.3.965 · Cited by 282
Mutagenic cost of ribonucleotides in bacterial DNA
Schroeder, J. W., Randall, J. R., Hirst, W. G., O’Donnell, M. E., & Simmons, L. A. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1710995114 · Cited by 37
Structural aspects of DNA repair and recombination in crop improvement
Verma, P., Tandon, R., Yadav, G., & Gaur, V. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.574549 · Cited by 29
Cresti, J. R., & Simmons, L. A. (2026) · Molecular Microbiology · doi:10.1111/mmi.70047 · Cited by 2
Metadata
- Authors
- Lahue, R. S., Au, K. G., & Modrich, P.
- Venue
- Science
- Published
- 1989-07-14
- Volume
- 245
- Issue
- 4914
- Pages
- 160-164
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2044198642
- Cited by
- 559
- References
- 0
- FWCI
- 4.84
- Type
- journal article
- Language
- en
- Open access
- closed
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