The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Role of NK1.1 + T Cells in a T H 2 Response and in Immunoglobulin E Production
Abstract
Immune responses dominated by interleukin-4 (IL-4)-producing T helper type 2 (T H 2) cells or by interferon γ (IFN-γ)-producing T helper type 1 (T H 1) cells express distinctive protection against infection with different pathogens. Interleukin-4 promotes the differentiation of naïve CD4 + T cells into IL-4 producers and suppresses their development into IFN-γ producers. CD1-specific splenic CD4 + NK1.1 + T cells, a numerically minor population, produced IL-4 promptly on in vivo stimulation. This T cell population was essential for the induction of IL-4-producing cells and for switching to immunoglobulin E, an IL-4-dependent event, in response to injection of antibodies to immunoglobulin D.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
IL‐4 directs the development of Th2‐like helper effectors
Swain, S. L., Weinberg, A. D., English, M., & Huston, G. (1990) · The Journal of Immunology · doi:10.4049/jimmunol.145.11.3796 · Cited by 1,254
Le Gros, G., Ben-Sasson, S. Z., Seder, R., Finkelman, F. D., & Paul, W. E. (1990) · The Journal of experimental medicine · doi:10.1084/jem.172.3.921 · Cited by 954
Self-citationFerrick, D. A., Schrenzel, M. D., Mulvania, T., Hsieh, B., Ferlin, W. G., & Lepper, H. (1995) · Nature · doi:10.1038/373255a0 · Cited by 662
Cited by
Alternative Activation of Macrophages: An Immunologic Functional Perspective
Martinez, F. O., Helming, L., & Gordon, S. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132532 · Cited by 2,745
IL-17 family cytokines and the expanding diversity of effector T cell lineages
Weaver, C. T., Hatton, R. D., Mangan, P. R., & Harrington, L. E. (2007) · Annual Review of Immunology · doi:10.1146/annurev.immunol.25.022106.141557 · Cited by 1,842
Cytokines Induce the Development of Functionally Heterogeneous T Helper Cell Subsets
O'Garra, A. (1998) · Immunity · doi:10.1016/s1074-7613(00)80533-6 · Cited by 1,533
Romagnani, S. (1997) · Immunology Today · doi:10.1016/s0167-5699(97)80019-9 · Cited by 1,078
Stevens, D. A., Moss, R. B., Kurup, V. P., Knutsen, A. P., Greenberger, P., Judson, M. A., Denning, D. W., Crameri, R., Brody, A. S., Light, M., et al. (2003) · Clinical Infectious Diseases · doi:10.1086/376525 · Cited by 790
Metadata
- Authors
- Yoshimoto, T., Bendelac, A., Watson, C., Hu-Li, J., & Paul, W. E.
- Venue
- Science
- Published
- 1995-12-15
- Volume
- 270
- Issue
- 5243
- Pages
- 1845-1847
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2001146686
- Cited by
- 496
- References
- 3
- FWCI
- 17.74
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Role of NK1.1 + T Cells in a T H 2 Response and in Immunoglobulin E Production. https://app.cochat.ai/papers/10.1126/science.270.5243.1845
- The paper
- Yoshimoto, T., Bendelac, A., Watson, C., Hu-Li, J., & Paul, W. E. (1995). Role of NK1.1 + T Cells in a T H 2 Response and in Immunoglobulin E Production. Science. https://doi.org/10.1126/science.270.5243.1845
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.