The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Population Biology of Antigen Presentation by MHC Class I Molecules
Abstract
In principle, the function of major histocompatibility complex (MHC) molecules is simple: to bind a peptide and engage a T cell. In practice, placing this function within the context of the immune response begs questions of population biology: How does the immune response emerge from the interactions among populations of peptides, T cells, and MHC molecules? Within a population of vertebrates, how does MHC polymorphism stamp individuality on the response? Does polymorphism confer differential advantages in responding to parasites? How are the pressures on the MHC reflected in turnover of alleles? The role of mutation, recombination, selection, and drift in the generation and maintenance of MHC class I polymorphism are considered.
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Bjorkman, P. J., Saper, M. A., Samraoui, B., Bennett, W. S., Strominger, J. L., & Wiley, D. C. (1987) · Nature · doi:10.1038/329512a0 · Cited by 2,377
STRUCTURE, FUNCTION, AND DIVERSITY OF CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULES
Bjorkman, P. J., & Parham, P. (1990) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.59.070190.001345 · Cited by 700
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Metadata
- Authors
- Parham, P., & Ohta, T.
- Venue
- Science
- Published
- 1996-04-05
- Volume
- 272
- Issue
- 5258
- Pages
- 67-74
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2014569071
- Cited by
- 655
- References
- 2
- FWCI
- 24.67
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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