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Control Strategies for Tuberculosis Epidemics: New Models for Old Problems
Abstract
Tuberculosis, although preventable and curable, causes more adult deaths than any other infectious disease. A theoretical framework for designing effective control strategies is developed and used to determine treatment levels for eradication, to assess the effects of noneradicating control, and to examine the global goals of the World Health Organization. The theory is extended to assess how suboptimal control programs contribute to the evolution of drug resistance. A new evaluation criterion is defined and used to suggest how control strategies can be improved. In order to control tuberculosis, treatment failure rates must be lower in developing countries than in developed countries.
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Citations
Cited by
VYNNYCKY, E., & FINE, P. E. M. (1997) · Epidemiology and Infection · doi:10.1017/s0950268897007917 · Cited by 555
Antimicrobial Use and Antimicrobial Resistance: A Population Perspective
Lipsitch, M., & Samore, M. H. (2002) · Emerging Infectious Diseases · doi:10.3201/eid0804.010312 · Cited by 497
Prospects for worldwide tuberculosis control under the WHO DOTS strategy
Dye, C., Garnett, G. P., Sleeman, K., & Williams, B. G. (1998) · The Lancet · doi:10.1016/s0140-6736(98)03199-7 · Cited by 462
Farmer, P., & Kim, J. Y. (1998) · BMJ · doi:10.1136/bmj.317.7159.671 · Cited by 256
Simulating the Effect of Quarantine on the Spread of the 1918–19 Flu in Central Canada
Sattenspiel, L. (2003) · Bulletin of Mathematical Biology · doi:10.1006/bulm.2002.0317 · Cited by 120
Metadata
- Authors
- Blower, S. M., Small, P. M., & Hopewell, P. C.
- Venue
- Science
- Published
- 1996-07-26
- Volume
- 273
- Issue
- 5274
- Pages
- 497-500
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2067900965
- Cited by
- 350
- References
- 0
- FWCI
- 12.85
- Type
- journal article
- Language
- en
- Open access
- closed
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- Blower, S. M., Small, P. M., & Hopewell, P. C. (1996). Control Strategies for Tuberculosis Epidemics: New Models for Old Problems. Science. https://doi.org/10.1126/science.273.5274.497
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.