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Cited by 328

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

KUZ, a Conserved Metalloprotease-Disintegrin Protein with Two Roles in Drosophila Neurogenesis

Rooke, Jenny, Pan, Duojia, Xu, Tian, Rubin, Gerald M.·1996·Science

Abstract

During neurogenesis in Drosophila both neurons and nonneuronal cells are produced from a population of initially equivalent cells. The kuzbanian ( kuz ) gene described here is essential for the partitioning of neural and nonneuronal cells during development of both the central and peripheral nervous systems in Drosophila . Mosaic analyses indicated that kuz is required for cells to receive signals inhibiting the neural fate. These analyses further revealed that the development of a neuron requires a kuz -mediated positive signal from neighboring cells. The kuz gene encodes a metalloprotease-disintegrin protein with a highly conserved bovine homolog, raising the possibility that kuz homologs may act in similar processes during mammalian neurogenesis.

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Metadata

Authors
Rooke, J., Pan, D., Xu, T., & Rubin, G. M.
Venue
Science
Published
1996-08-30
Volume
273
Issue
5279
Pages
1227-1231
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2015764953
Cited by
328
References
2
FWCI
11.75
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: KUZ, a Conserved Metalloprotease-Disintegrin Protein with Two Roles in Drosophila Neurogenesis. https://app.cochat.ai/papers/10.1126/science.273.5279.1227
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Rooke, J., Pan, D., Xu, T., & Rubin, G. M. (1996). KUZ, a Conserved Metalloprotease-Disintegrin Protein with Two Roles in Drosophila Neurogenesis. Science. https://doi.org/10.1126/science.273.5279.1227

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.