The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Intestinal Secretory Defects and Dwarfism in Mice Lacking cGMP-Dependent Protein Kinase II
Abstract
Cyclic guanosine 3′,5′-monophosphate (cGMP)-dependent protein kinases (cGKs) mediate cellular signaling induced by nitric oxide and cGMP. Mice deficient in the type II cGK were resistant to Escherichia coli STa, an enterotoxin that stimulates cGMP accumulation and intestinal fluid secretion. The cGKII-deficient mice also developed dwarfism that was caused by a severe defect in endochondral ossification at the growth plates. These results indicate that cGKII plays a central role in diverse physiological processes.
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Cites
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Cited by
Pfeifer, A., Ikawa, M., Dayn, Y., & Verma, I. M. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.251682798 · Cited by 522
Self-citationRising behind NO: cGMP-dependent protein kinases
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Self-citationCyclic Nucleotide-Dependent Protein Kinases: Intracellular Receptors for cAMP and cGMP Action
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Castro, J., Harrington, A. M., Hughes, P. A., Martin, C. M., Ge, P., Shea, C. M., Jin, H., Jacobson, S., Hannig, G., Mann, E., et al. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.08.017 · Cited by 295
Metadata
- Authors
- Pfeifer, A., Aszódi, A., Seidler, U., Ruth, P., Hofmann, F., & Fässler, R.
- Venue
- Science
- Published
- 1996-12-20
- Volume
- 274
- Issue
- 5295
- Pages
- 2082-2086
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1975748795
- Cited by
- 403
- References
- 19
- FWCI
- 7.55
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Intestinal Secretory Defects and Dwarfism in Mice Lacking cGMP-Dependent Protein Kinase II. https://app.cochat.ai/papers/10.1126/science.274.5295.2082
- The paper
- Pfeifer, A., Aszódi, A., Seidler, U., Ruth, P., Hofmann, F., & Fässler, R. (1996). Intestinal Secretory Defects and Dwarfism in Mice Lacking cGMP-Dependent Protein Kinase II. Science. https://doi.org/10.1126/science.274.5295.2082
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
