The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Peptide Binding and Release by Proteins Implicated as Catalysts of Protein Assembly
Abstract
Two members of the hsp70 family, termed hsc70 and BiP, have been implicated in promoting protein folding and assembly processes in the cytoplasm and the lumen of the endoplasmic reticulum, respectively. Short hydrophilic (8 to 25 residues) synthetic peptides have now been tested as possible mimics of polypeptide chain substrates to help define an enzymatic basis for these activities. Both BiP and hsc70 have specific peptide binding sites. Peptide binding elicits hydrolysis of adenosine triphosphate, with the subsequent release of bound peptide.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961
Principles that Govern the Folding of Protein Chains
Anfinsen, C. B. (1973) · Science · doi:10.1126/science.181.4096.223 · Cited by 7,096
Cited by
Rosenzweig, R., Nillegoda, N. B., Mayer, M. P., & Bukau, B. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0133-3 · Cited by 1,285
Structural Analysis of Substrate Binding by the Molecular Chaperone DnaK
Zhu, X., Zhao, X., Burkholder, W. F., Gragerov, A., Ogata, C. M., Gottesman, M. E., & Hendrickson, W. A. (1996) · Science · doi:10.1126/science.272.5268.1606 · Cited by 1,258
Martin, J., Langer, T., Boteva, R., Schramel, A., Horwich, A. L., & Hartl, F.-U. (1991) · Nature · doi:10.1038/352036a0 · Cited by 854
Role and regulation of the ER chaperone BiP
Gething, M.-J. (1999) · Seminars in Cell & Developmental Biology · doi:10.1006/scdb.1999.0318 · Cited by 555
Abravaya, K., Myers, M. P., Murphy, S. P., & Morimoto, R. I. (1992) · Genes & Development · doi:10.1101/gad.6.7.1153 · Cited by 538
Metadata
- Authors
- Flynn, G. C., Chappell, T. G., & Rothman, J. E.
- Venue
- Science
- Published
- 1989-07-28
- Volume
- 245
- Issue
- 4916
- Pages
- 385-390
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2092198909
- Cited by
- 753
- References
- 2
- FWCI
- 23.81
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Peptide Binding and Release by Proteins Implicated as Catalysts of Protein Assembly. https://app.cochat.ai/papers/10.1126/science.2756425
- The paper
- Flynn, G. C., Chappell, T. G., & Rothman, J. E. (1989). Peptide Binding and Release by Proteins Implicated as Catalysts of Protein Assembly. Science. https://doi.org/10.1126/science.2756425
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
