The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Patterned Delivery of Immunoglobulins to Surfaces Using Microfluidic Networks
Abstract
Microfluidic networks (μFNs) were used to pattern biomolecules with high resolution on a variety of substrates (gold, glass, or polystyrene). Elastomeric μFNs localized chemical reactions between the biomolecules and the surface, requiring only microliters of reagent to cover square millimeter–sized areas. The networks were designed to ensure stability and filling of the μFN and allowed a homogeneous distribution and robust attachment of material to the substrate along the conduits in the μFN. Immunoglobulins patterned on substrates by means of μFNs remained strictly confined to areas enclosed by the network with submicron resolution and were viable for subsequent use in assays. The approach is simple and general enough to suggest a practical way to incorporate biological material on technological substrates.
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Cites
Light-Directed, Spatially Addressable Parallel Chemical Synthesis
Fodor, S. P. A., Read, J. L., Pirrung, M. C., Stryer, L., Lu, A. T., & Solas, D. (1991) · Science · doi:10.1126/science.1990438 · Cited by 2,696
Engineering cell shape and function
Singhvi, R., Kumar, A., Lopez, G. P., Stephanopoulos, G. N., Wang, D. I. C., Whitesides, G. M., & Ingber, D. E. (1994) · Science · doi:10.1126/science.8171320 · Cited by 1,453
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications
(1992) · Springer eBooks · doi:10.1007/978-1-4899-0703-5 · Cited by 1,420
Polymer microstructures formed by moulding in capillaries
Kim, E., Xia, Y., & Whitesides, G. M. (1995) · Nature · doi:10.1038/376581a0 · Cited by 878
Complex Optical Surfaces Formed by Replica Molding Against Elastomeric Masters
Xia, Y., Kim, E., Zhao, X.-M., Rogers, J. A., Prentiss, M., & Whitesides, G. M. (1996) · Science · doi:10.1126/science.273.5273.347 · Cited by 643
Mrksich, M., Chen, C. S., Xia, Y., Dike, L. E., Ingber, D. E., & Whitesides, G. M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.20.10775 · Cited by 425
Stenger, D. A., Georger, J. H., Dulcey, C. S., Hickman, J. J., Rudolph, A. S., Nielsen, T. B., McCort, S. M., & Calvert, J. M. (1992) · Journal of the American Chemical Society · doi:10.1021/ja00048a013 · Cited by 297
Lopez, G. P., Biebuyck, H. A., Harter, R., Kumar, A., & Whitesides, G. M. (1993) · Journal of the American Chemical Society · doi:10.1021/ja00076a038 · Cited by 171
Self-citation
Cited by
Fabrication of microfluidic systems in poly(dimethylsiloxane)
McDonald, J. C., Duffy, D. C., Anderson, J. R., Chiu, D. T., Wu, H., Schueller, O. J. A., & Whitesides, G. M. (2000) · Electrophoresis · doi:10.1002/(sici)1522-2683(20000101)21:1<27::aid-elps27>3.0.co;2-c · Cited by 3,329
Seemann, R., Brinkmann, M., Pfohl, T., & Herminghaus, S. (2012) · Reports on Progress in Physics · doi:10.1088/0034-4885/75/1/016601 · Cited by 1,049
Bhatia, S. N., Balis, U. J., Yarmush, M. L., & Toner, M. (1999) · The FASEB Journal · doi:10.1096/fasebj.13.14.1883 · Cited by 890
Abgrall, P., & Gué, A.-M. (2007) · Journal of Micromechanics and Microengineering · doi:10.1088/0960-1317/17/5/r01 · Cited by 561
Torisawa, Y.-S., Shiku, H., Yasukawa, T., Nishizawa, M., & Matsue, T. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.05.028 · Cited by 124
Metadata
- Authors
- Delamarche, E., Bernard, A., Schmid, H., Michel, B., & Biebuyck, H.
- Venue
- Science
- Published
- 1997-05-02
- Volume
- 276
- Issue
- 5313
- Pages
- 779-781
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1978027717
- Cited by
- 678
- References
- 8
- FWCI
- 29.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- Delamarche, E., Bernard, A., Schmid, H., Michel, B., & Biebuyck, H. (1997). Patterned Delivery of Immunoglobulins to Surfaces Using Microfluidic Networks. Science. https://doi.org/10.1126/science.276.5313.779
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
