The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Forward and Backward Propagation of Dendritic Impulses and Their Synaptic Control in Mitral Cells
Abstract
The site of impulse initiation is crucial for the integrative actions of mammalian central neurons, but this question is currently controversial. Some recent studies support classical evidence that the impulse always arises in the soma-axon hillock region, with back-propagation through excitable dendrites, whereas others indicate that the dendrites are sufficiently excitable to initiate impulses that propagate forward along the dendrite to the soma-axon hillock. This issue has been addressed in the olfactory mitral cell, in which excitatory synaptic input is restricted to the distal tuft of a single primary dendrite. In rat olfactory bulb slices, dual whole cell recordings were made at or near the soma and from distal sites on the primary dendrite. The results show that the impulse can be initiated in either the soma-axon hillock or in the distal primary dendrite, and that the initiation site is controlled physiologically by the excitatory synaptic inputs to the distal tuft and inhibitory synaptic inputs near the soma.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Synaptically Controlled, Associative Signal for Hebbian Plasticity in Hippocampal Neurons
Magee, J. C., & Johnston, D. (1997) · Science · doi:10.1126/science.275.5297.209 · Cited by 1,315
DeFelipe, J., & Fariñas, I. (1992) · Progress in Neurobiology · doi:10.1016/0301-0082(92)90015-7 · Cited by 975
Activity-Dependent Action Potential Invasion and Calcium Influx into Hippocampal CA1 Dendrites
Spruston, N., Schiller, Y., Stuart, G., & Sakmann, B. (1995) · Science · doi:10.1126/science.7716524 · Cited by 826
In vivo dendritic calcium dynamics in neocortical pyramidal neurons
Svoboda, K., Denk, W., Kleinfeld, D., & Tank, D. W. (1997) · Nature · doi:10.1038/385161a0 · Cited by 815
Stuart, G. J., Dodt, H. U., & Sakmann, B. (1993) · Pfl�gers Archiv European Journal of Physiology · doi:10.1007/bf00374949 · Cited by 803
Action potential initiation and backpropagation in neurons of the mammalian CNS
Stuart, G., Spruston, N., Sakmann, B., & Häusser, M. (1997) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)10075-8 · Cited by 768
Rall, W., & Shepherd, G. M. (1968) · Journal of Neurophysiology · doi:10.1152/jn.1968.31.6.884 · Cited by 710
Self-citationDendrodendritic synaptic pathway for inhibition in the olfactory bulb
Rall, W., Shepherd, G. M., Reese, T. S., & Brightman, M. W. (1966) · Experimental Neurology · doi:10.1016/0014-4886(66)90023-9 · Cited by 676
Self-citationELECTROPHYSIOLOGY OF HIPPOCAMPAL NEURONS: IV. FAST PREPOTENTIALS
Spencer, W. A., & Kandel, E. R. (1961) · Journal of Neurophysiology · doi:10.1152/jn.1961.24.3.272 · Cited by 499
A model of spike initiation in neocortical pyramidal neurons
Mainen, Z. F., Joerges, J., Huguenard, J. R., & Sejnowski, T. J. (1995) · Neuron · doi:10.1016/0896-6273(95)90020-9 · Cited by 430
Cited by
Propagation of action potentials in dendrites depends on dendritic morphology
Vetter, P., Roth, A., & Häusser, M. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.2.926 · Cited by 598
Klausberger, T., Marton, L. F., O'Neill, J., Huck, J. H. J., Dalezios, Y., Fuentealba, P., Suen, W. Y., Papp, E., Kaneko, T., Watanabe, M., et al. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3269-05.2005 · Cited by 469
Odor Encoding as an Active, Dynamical Process: Experiments, Computation, and Theory
Laurent, G., Stopfer, M., Friedrich, R. W., Rabinovich, M. I., Volkovskii, A., & Abarbanel, H. D. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.263 · Cited by 459
Klausberger, T., Márton, L. F., Baude, A., Roberts, J. D. B., Magill, P. J., & Somogyi, P. (2004) · Nature Neuroscience · doi:10.1038/nn1159 · Cited by 393
Distal Initiation and Active Propagation of Action Potentials in Interneuron Dendrites
Martina, M., Vida, I., & Jonas, P. (2000) · Science · doi:10.1126/science.287.5451.295 · Cited by 375
Metadata
- Authors
- Chen, W. R., Midtgaard, J., & Shepherd, G. M.
- Venue
- Science
- Published
- 1997-10-17
- Volume
- 278
- Issue
- 5337
- Pages
- 463-467
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2091828531
- Cited by
- 256
- References
- 26
- FWCI
- 4.68
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Forward and Backward Propagation of Dendritic Impulses and Their Synaptic Control in Mitral Cells. https://app.cochat.ai/papers/10.1126/science.278.5337.463
- The paper
- Chen, W. R., Midtgaard, J., & Shepherd, G. M. (1997). Forward and Backward Propagation of Dendritic Impulses and Their Synaptic Control in Mitral Cells. Science. https://doi.org/10.1126/science.278.5337.463
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
