The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Gene Families: The Taxonomy of Protein Paralogs and Chimeras
Abstract
Ancient duplications and rearrangements of protein-coding segments have resulted in complex gene family relationships. Duplications can be tandem or dispersed and can involve entire coding regions or modules that correspond to folded protein domains. As a result, gene products may acquire new specificities, altered recognition properties, or modified functions. Extreme proliferation of some families within an organism, perhaps at the expense of other families, may correspond to functional innovations during evolution. The underlying processes are still at work, and the large fraction of human and other genomes consisting of transposable elements may be a manifestation of the evolutionary benefits of genomic flexibility.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Kashlna, A. S., Baskin, R. J., Cole, D. G., Wedaman, K. P., Saxton, W. M., & Scholey, J. M. (1996) · Nature · doi:10.1038/379270a0 · Cited by 352
MOLECULAR GENETICS OF HUMAN VISUAL PIGMENTS
Nathans, J., Merbs, S. L., Sung, C.-H., Weitz, C. J., & Wang, Y. (1992) · Annual Review of Genetics · doi:10.1146/annurev.ge.26.120192.002155 · Cited by 185
Cited by
OrthoMCL: Identification of Ortholog Groups for Eukaryotic Genomes
Li, L., Stoeckert, C. J., & Roos, D. S. (2003) · Genome Research · doi:10.1101/gr.1224503 · Cited by 5,707
Eddy, S. R. (1998) · Bioinformatics · doi:10.1093/bioinformatics/14.9.755 · Cited by 5,515
SHEEHAN, D., MEADE, G., FOLEY, V. M., & DOWD, C. A. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3600001 · Cited by 3,057
Cannon, S. B., Mitra, A., Baumgarten, A., Young, N. D., & May, G. (2004) · BMC Plant Biology · doi:10.1186/1471-2229-4-10 · Cited by 2,372
Kang, J., Park, J., Choi, H., Burla, B., Kretzschmar, T., Lee, Y., & Martinoia, E. (2011) · The Arabidopsis Book · doi:10.1199/tab.0153 · Cited by 573
Metadata
- Authors
- Henikoff, S., Greene, E. A., Pietrokovski, S., Bork, P., Attwood, T. K., & Hood, L.
- Venue
- Science
- Published
- 1997-10-24
- Volume
- 278
- Issue
- 5338
- Pages
- 609-614
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1578832578
- Cited by
- 389
- References
- 2
- FWCI
- 49.51
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Gene Families: The Taxonomy of Protein Paralogs and Chimeras. https://app.cochat.ai/papers/10.1126/science.278.5338.609
- The paper
- Henikoff, S., Greene, E. A., Pietrokovski, S., Bork, P., Attwood, T. K., & Hood, L. (1997). Gene Families: The Taxonomy of Protein Paralogs and Chimeras. Science. https://doi.org/10.1126/science.278.5338.609
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
