The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Characterization of an Avian Influenza A (H5N1) Virus Isolated from a Child with a Fatal Respiratory Illness
Abstract
An avian H5N1 influenza A virus (A/Hong Kong/156/97) was isolated from a tracheal aspirate obtained from a 3-year-old child in Hong Kong with a fatal illness consistent with influenza. Serologic analysis indicated the presence of an H5 hemagglutinin. All eight RNA segments were derived from an avian influenza A virus. The hemagglutinin contained multiple basic amino acids adjacent to the cleavage site, a feature characteristic of highly pathogenic avian influenza A viruses. The virus caused 87.5 to 100 percent mortality in experimentally inoculated White Plymouth Rock and White Leghorn chickens. These results may have implications for global influenza surveillance and planning for pandemic influenza.
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Citations
Cites
Initial Genetic Characterization of the 1918 “Spanish” Influenza Virus
Taubenberger, J. K., Reid, A. H., Krafft, A. E., Bijwaard, K. E., & Fanning, T. G. (1997) · Science · doi:10.1126/science.275.5307.1793 · Cited by 715
Cited by
Emerging Infectious Diseases of Wildlife-- Threats to Biodiversity and Human Health
Daszak, P., Cunningham, A. A., & Hyatt, A. D. (2000) · Science · doi:10.1126/science.287.5452.443 · Cited by 4,885
Cheung, C., Poon, L., Lau, A., Luk, W., Lau, Y., Shortridge, K., Gordon, S., Guan, Y., & Peiris, J. (2002) · The Lancet · doi:10.1016/s0140-6736(02)11772-7 · Cited by 889
Koopmans, M., Wilbrink, B., Conyn, M., Natrop, G., van der Nat, H., Vennema, H., Meijer, A., van Steenbergen, J., Fouchier, R., Osterhaus, A., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)15589-x · Cited by 837
Role of hemagglutinin cleavage for the pathogenicity of influenza virus.
Steinhauer, D. A. (1999) · Virology · doi:10.1006/viro.1999.9716 · Cited by 663
Origin and evolution of the 1918 “Spanish” influenza virus hemagglutinin gene
Reid, A. H., Fanning, T. G., Hultin, J. V., & Taubenberger, J. K. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.4.1651 · Cited by 607
Metadata
- Authors
- Subbarao, K., Klimov, A., Katz, J., Regnery, H., Lim, W., Hall, H., Perdue, M., Swayne, D., Bender, C., Huang, J., Hemphill, M., Rowe, T., Shaw, M., Xu, X., Fukuda, K., & Cox, N.
- Venue
- Science
- Published
- 1998-01-16
- Volume
- 279
- Issue
- 5349
- Pages
- 393-396
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2163960578
- Cited by
- 1,362
- References
- 1
- FWCI
- 53.98
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Characterization of an Avian Influenza A (H5N1) Virus Isolated from a Child with a Fatal Respiratory Illness. https://app.cochat.ai/papers/10.1126/science.279.5349.393
- The paper
- Subbarao, K., Klimov, A., Katz, J., Regnery, H., Lim, W., Hall, H., Perdue, M., Swayne, D., Bender, C., Huang, J., Hemphill, M., Rowe, T., Shaw, M., Xu, X., Fukuda, K., & Cox, N. (1998). Characterization of an Avian Influenza A (H5N1) Virus Isolated from a Child with a Fatal Respiratory Illness. Science. https://doi.org/10.1126/science.279.5349.393
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
