The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Interaction of a Golgi-Associated Kinesin-Like Protein with Rab6
Abstract
Rab guanosine triphosphatases regulate vesicular transport and membrane traffic within eukaryotic cells. Here, a kinesin-like protein that interacts with guanosine triphosphate (GTP)–bound forms of Rab6 was identified. This protein, termed Rabkinesin-6, was localized to the Golgi apparatus and shown to play a role in the dynamics of this organelle. The carboxyl-terminal domain of Rabkinesin-6, which contains the Rab6-interacting domain, inhibited the effects of Rab6-GTP on intracellular transport. Thus, a molecular motor is a potential effector of a Rab protein, and coordinated action between members of these two families of proteins could control membrane dynamics and directional vesicular traffic.
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Cites
Predicting coiled coils from protein sequences.
Lupas, A., Van Dyke, M., & Stock, J. (1991) · Science · doi:10.1126/science.252.5009.1162 · Cited by 3,953
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The carboxyl-terminal domain of kinesin heavy chain is important for membrane binding
Skoufias, D. A., Cole, D. G., Wedaman, K. P., & Scholey, J. M. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)42281-2 · Cited by 110
Cited by
Rab GTPases as coordinators of vesicle traffic
Stenmark, H. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2728 · Cited by 3,413
Rab proteins as membrane organizers
Zerial, M., & McBride, H. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35052055 · Cited by 3,381
Kinesin superfamily motor proteins and intracellular transport
Hirokawa, N., Noda, Y., Tanaka, Y., & Niwa, S. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2774 · Cited by 1,859
Role of Rab GTPases in Membrane Traffic and Cell Physiology
Hutagalung, A. H., & Novick, P. J. (2011) · Physiological Reviews · doi:10.1152/physrev.00059.2009 · Cited by 1,460
Rab7: A Key to Lysosome Biogenesis
Bucci, C., Thomsen, P., Nicoziani, P., McCarthy, J., & van Deurs, B. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.2.467 · Cited by 1,085
Metadata
- Authors
- Echard, A., Jollivet, F., Martinez, O., Lacapère, J.-J., Rousselet, A., Janoueix-Lerosey, I., & Goud, B.
- Venue
- Science
- Published
- 1998-01-23
- Volume
- 279
- Issue
- 5350
- Pages
- 580-585
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2100096634
- Cited by
- 518
- References
- 3
- FWCI
- 18.13
- Type
- journal article
- Language
- en
- Open access
- closed
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- Echard, A., Jollivet, F., Martinez, O., Lacapère, J.-J., Rousselet, A., Janoueix-Lerosey, I., & Goud, B. (1998). Interaction of a Golgi-Associated Kinesin-Like Protein with Rab6. Science. https://doi.org/10.1126/science.279.5350.580
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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