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G Proteins and Small GTPases: Distant Relatives Keep in Touch
Abstract
Both low molecular weight G proteins and the larger heterotrimeric G proteins are switched on and off by binding the nucleotide GTP. New results in this issue by Kosaza et al. and Hart et al. show that these two distant relatives actually regulate one another. Hall explains in his commentary that this advance is more than just a family reunion and actually reveals the mechanism by which many fundamental cell processes that alter cell shape are regulated, including gastrulation.
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Cited by
Sphingosine 1-Phosphate, a Key Cell Signaling Molecule
Spiegel, S., & Milstien, S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.r200007200 · Cited by 555
Simmons, D. A., Casale, M., Alcon, B., Pham, N., Narayan, N., & Lynch, G. (2007) · Glia · doi:10.1002/glia.20526 · Cited by 277
Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide
Berry, C., Touyz, R., Dominiczak, A. F., Webb, R. C., & Johns, D. G. (2001) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2001.281.6.h2337 · Cited by 259
Rolli-Derkinderen, M., Sauzeau, V., Boyer, L., Lemichez, E., Baron, C., Henrion, D., Loirand, G., & Pacaud, P. (2005) · Circulation Research · doi:10.1161/01.res.0000170084.88780.ea · Cited by 147
Migeotte, I., Omelchenko, T., Hall, A., & Anderson, K. V. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000442 · Cited by 114
Self-citation
Metadata
- Authors
- Hall, A.
- Venue
- Science
- Published
- 1998-06-26
- Volume
- 280
- Issue
- 5372
- Pages
- 2074-2075
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1502326664
- Cited by
- 217
- References
- 0
- FWCI
- 5.18
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
