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Cited by 15,926

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Embryonic Stem Cell Lines Derived from Human Blastocysts

Thomson, James A., Itskovitz-Eldor, Joseph, Shapiro, Sander S., Waknitz, Michelle A., Swiergiel, Jennifer J., Marshall, Vivienne S., Jones, Jeffrey M.·1998·Science

Abstract

Human blastocyst-derived, pluripotent cell lines are described that have normal karyotypes, express high levels of telomerase activity, and express cell surface markers that characterize primate embryonic stem cells but do not characterize other early lineages. After undifferentiated proliferation in vitro for 4 to 5 months, these cells still maintained the developmental potential to form trophoblast and derivatives of all three embryonic germ layers, including gut epithelium (endoderm); cartilage, bone, smooth muscle, and striated muscle (mesoderm); and neural epithelium, embryonic ganglia, and stratified squamous epithelium (ectoderm). These cell lines should be useful in human developmental biology, drug discovery, and transplantation medicine.

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Crossref · 10.1126/science.282.5391.1145

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Metadata

Authors
Thomson, J. A., Itskovitz-Eldor, J., Shapiro, S. S., Waknitz, M. A., Swiergiel, J. J., Marshall, V. S., & Jones, J. M.
Venue
Science
Published
1998-11-06
Volume
282
Issue
5391
Pages
1145-1147
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2086943348
Cited by
15,926
References
4
FWCI
42.55
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Embryonic Stem Cell Lines Derived from Human Blastocysts. https://app.cochat.ai/papers/10.1126/science.282.5391.1145
The paper
Thomson, J. A., Itskovitz-Eldor, J., Shapiro, S. S., Waknitz, M. A., Swiergiel, J. J., Marshall, V. S., & Jones, J. M. (1998). Embryonic Stem Cell Lines Derived from Human Blastocysts. Science. https://doi.org/10.1126/science.282.5391.1145

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.