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The Elastin Receptor: A Galactoside-Binding Protein
Abstract
The elastin receptor complex contains a component of 67 kilodaltons that binds to a glycoconjugate affinity column containing β-galactoside residues and is eluted from this column with lactose. This protein component is also released from the surface of cultured chondroblasts by incubation with lactose, and its association with immobilized elastin is inhibited by lactose. Since lactose also blocks elastic fiber formation by cultured chondroblasts, the galactoside-binding property of the elastin receptor is implicated in this process.
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Citations
Cited by
Elastin: molecular description and function
Debelle, L., & Tamburro, A. M. (1999) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(98)00098-3 · Cited by 545
Hinek, A., Pshezhetsky, A. V., von Itzstein, M., & Starcher, B. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m508736200 · Cited by 176
Self-citationElastin signaling in wound repair
Almine, J. F., Wise, S. G., & Weiss, A. S. (2012) · Birth Defects Research Part C: Embryo Today: Reviews · doi:10.1002/bdrc.21016 · Cited by 155
Tropoelastin Interacts with Cell-surface Glycosaminoglycans via Its COOH-terminal Domain
Broekelmann, T. J., Kozel, B. A., Ishibashi, H., Werneck, C. C., Keeley, F. W., Zhang, L., & Mecham, R. P. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m507309200 · Cited by 149
Self-citationAntibodies to β1‐integrins cause alterations of aortic vasculogenesis, in vivo
Drake, C. J., Davis, L. A., & Little, C. D. (1992) · Developmental Dynamics · doi:10.1002/aja.1001930111 · Cited by 124
Metadata
- Authors
- Hinek, A., Wrenn, D. S., Mecham, R. P., & Barondes, S. H.
- Venue
- Science
- Published
- 1988-03-25
- Volume
- 239
- Issue
- 4847
- Pages
- 1539-1541
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2067245236
- Cited by
- 316
- References
- 0
- FWCI
- 7.97
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The Elastin Receptor: A Galactoside-Binding Protein. https://app.cochat.ai/papers/10.1126/science.2832941
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- Hinek, A., Wrenn, D. S., Mecham, R. P., & Barondes, S. H. (1988). The Elastin Receptor: A Galactoside-Binding Protein. Science. https://doi.org/10.1126/science.2832941
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
