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Cited by 583

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

X-ray Crystal Structures of 70 S Ribosome Functional Complexes

Cate, Jamie H., Yusupov, Marat M., Yusupova, Gulnara Zh., Earnest, Thomas N., Noller, Harry F.·1999·Science

Abstract

Structures of 70 S ribosome complexes containing messenger RNA and transfer RNA (tRNA), or tRNA analogs, have been solved by x-ray crystallography at up to 7.8 angstrom resolution. Many details of the interactions between tRNA and the ribosome, and of the packing arrangements of ribosomal RNA (rRNA) helices in and between the ribosomal subunits, can be seen. Numerous contacts are made between the 30 S subunit and the P-tRNA anticodon stem-loop; in contrast, the anticodon region of A-tRNA is much more exposed. A complex network of molecular interactions suggestive of a functional relay is centered around the long penultimate stem of 16 S rRNA at the subunit interface, including interactions involving the “switch” helix and decoding site of 16 S rRNA, and RNA bridges from the 50 S subunit.

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Metadata

Authors
Cate, J. H., Yusupov, M. M., Yusupova, G. Z., Earnest, T. N., & Noller, H. F.
Venue
Science
Published
1999-09-24
Volume
285
Issue
5436
Pages
2095-2104
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2045690036
Cited by
583
References
1
FWCI
28.06
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: X-ray Crystal Structures of 70 S Ribosome Functional Complexes. https://app.cochat.ai/papers/10.1126/science.285.5436.2095
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Cate, J. H., Yusupov, M. M., Yusupova, G. Z., Earnest, T. N., & Noller, H. F. (1999). X-ray Crystal Structures of 70 S Ribosome Functional Complexes. Science. https://doi.org/10.1126/science.285.5436.2095

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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