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A Sting in the Tail of Electron Tracks
Abstract
It has always been thought that the type of DNA damage that cells find hard to repair is caused by high-energy electrons with the ability to ionize the components of DNA. In a Perspective, [Michael and O'Neill][1] discuss new findings ([ BoudaA¯ffa et al. ][2]) showing that one low-energy electron can cause long-lasting damage to DNA by inducing a multiple lesion that may be very difficult for the cell to repair. [1]: http://www.sciencemag.org/cgi/content/full/287/5458/1603 [2]: http://www.sciencemag.org/cgi/content/short/287/5458/1658
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Citations
Cited by
Alizadeh, E., Orlando, T. M., & Sanche, L. (2015) · Annual Review of Physical Chemistry · doi:10.1146/annurev-physchem-040513-103605 · Cited by 490
Friedland, W., Dingfelder, M., Kundrát, P., & Jacob, P. (2011) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/j.mrfmmm.2011.01.003 · Cited by 386
Simulation of DNA Damage after Proton Irradiation
Friedland, W., Jacob, P., Bernhardt, P., Paretzke, H. G., & Dingfelder, M. (2003) · Radiation Research · doi:10.1667/0033-7587(2003)159[0401:soddap]2.0.co;2 · Cited by 264
Electron-Induced Elimination of the Bromide Anion from Brominated Nucleobases. A Computational Study
Chomicz, L., Rak, J., & Storoniak, P. (2012) · The Journal of Physical Chemistry B · doi:10.1021/jp3008738 · Cited by 256
Alloni, D., Campa, A., Friedland, W., Mariotti, L., & Ottolenghi, A. (2012) · International Journal of Radiation Biology · doi:10.3109/09553002.2011.627976 · Cited by 58
Metadata
- Authors
- Michael, B. D., & O'Neill, P.
- Venue
- Science
- Published
- 2000-03-03
- Volume
- 287
- Issue
- 5458
- Pages
- 1603-1604
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1603398525
- Cited by
- 229
- References
- 0
- FWCI
- 1.35
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
