The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Molecular Linkage Underlying Microtubule Orientation Toward Cortical Sites in Yeast
Abstract
Selective microtubule orientation toward spatially defined cortical sites is critical to polarized cellular processes as diverse as axon outgrowth and T cell cytotoxicity. In yeast, oriented cytoplasmic microtubules align the mitotic spindle between mother and bud. The cortical marker protein Kar9 localizes to the bud tip and is required for the orientation of microtubules toward this region. Here, we show that Kar9 directs microtubule orientation by acting through Bim1, a conserved microtubule-binding protein. Bim1 homolog EB1 was originally identified through its interaction with adenomatous polyposis coli (APC) tumor suppressor, raising the possibility that an APC-EB1 linkage orients microtubules in higher cells.
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Citations
Cites
Dynamic instability of microtubule growth
Mitchison, T., & Kirschner, M. (1984) · Nature · doi:10.1038/312237a0 · Cited by 3,337
Goode, B., & Feinstein, S. (1994) · The Journal of cell biology · doi:10.1083/jcb.124.5.769 · Cited by 399
Cited by
Yeast formins regulate cell polarity by controlling the assembly of actin cables
Sagot, I., Klee, S. K., & Pellman, D. (2002) · Nature Cell Biology · doi:10.1038/ncb719 · Cited by 408
Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle
Rogers, S. L., Rogers, G. C., Sharp, D. J., & Vale, R. D. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200202032 · Cited by 408
Beyond polymer polarity: how the cytoskeleton builds a polarized cell
Li, R., & Gundersen, G. G. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2522 · Cited by 379
MECHANISMS OF POLARIZED GROWTH AND ORGANELLE SEGREGATION IN YEAST
Pruyne, D., Legesse-Miller, A., Gao, L., Dong, Y., & Bretscher, A. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.010403.103108 · Cited by 366
Comparative Analysis of Cytokinesis in Budding Yeast, Fission Yeast and Animal Cells
Balasubramanian, M. K., Bi, E., & Glotzer, M. (2004) · Current Biology · doi:10.1016/j.cub.2004.09.022 · Cited by 354
Metadata
- Authors
- Korinek, W. S., Copeland, M. J., Chaudhuri, A., & Chant, J.
- Venue
- Science
- Published
- 2000-03-24
- Volume
- 287
- Issue
- 5461
- Pages
- 2257-2259
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2061653995
- Cited by
- 199
- References
- 2
- FWCI
- 12.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- Korinek, W. S., Copeland, M. J., Chaudhuri, A., & Chant, J. (2000). Molecular Linkage Underlying Microtubule Orientation Toward Cortical Sites in Yeast. Science. https://doi.org/10.1126/science.287.5461.2257
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
