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Cited by 917

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ORCA3, a Jasmonate-Responsive Transcriptional Regulator of Plant Primary and Secondary Metabolism

van der Fits, Leslie, Memelink, Johan·2000·Science

Abstract

Biosynthesis of many classes of secondary metabolites in plants is induced by the stress hormone jasmonate. The gene for ORCA3, a jasmonate-responsive APETALA2 (AP2)-domain transcription factor from Catharanthus roseus , was isolated by transferred DNA activation tagging. Orca3 overexpression resulted in enhanced expression of several metabolite biosynthetic genes and, consequently, in increased accumulation of terpenoid indole alkaloids. Regulation of metabolite biosynthetic genes by jasmonate-responsive AP2-domain transcription factors may link plant stress responses to changes in metabolism.

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Metadata

Authors
van der Fits, L., & Memelink, J.
Venue
Science
Published
2000-07-14
Volume
289
Issue
5477
Pages
295-297
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2117856189
Cited by
917
References
0
FWCI
7.77
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: ORCA3, a Jasmonate-Responsive Transcriptional Regulator of Plant Primary and Secondary Metabolism. https://app.cochat.ai/papers/10.1126/science.289.5477.295
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van der Fits, L., & Memelink, J. (2000). ORCA3, a Jasmonate-Responsive Transcriptional Regulator of Plant Primary and Secondary Metabolism. Science. https://doi.org/10.1126/science.289.5477.295

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.