The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
A Single Receptor Binds Both Insulin-Like Growth Factor II and Mannose-6-Phosphate
Abstract
Amino acid sequences deduced from rat complementary DNA clones encoding the insulin-like growth factor II (IGF-II) receptor closely resemble those of the bovine cation-independent mannose-6-phosphate receptor (Man-6-P receptor CI ), suggesting they are identical structures. It is also shown that IGF-II receptors are adsorbed by immobilized pentamannosyl-6-phosphate and are specifically eluted with Man-6-P. Furthermore, Man-6-P specifically increases by about two times the apparent affinity of the purified rat placental receptor for 125 I-labeled IGF-II. These results indicate that the type II IGF receptor contains cooperative, high-affinity binding sites for both IGF-II and Man-6-P-containing proteins.
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Cites
Ellis, L., Clauser, E., Morgan, D. O., Edery, M., Roth, R. A., & Rutter, W. J. (1986) · Cell · doi:10.1016/0092-8674(86)90786-5 · Cited by 1,070
Chou, C. K., Dull, T. J., Russell, D. S., Gherzi, R., Lebwohl, D., Ullrich, A., & Rosen, O. M. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75716-0 · Cited by 640
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Czech, M. P. (1989) · Cell · doi:10.1016/0092-8674(89)90281-x · Cited by 377
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Barondes, S. H. (1988) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(88)90235-6 · Cited by 334
Mannose 6-phosphate receptors in sorting and transport of lysosomal enzymes
Hille-Rehfeld, A. (1995) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(95)00004-b · Cited by 249
Ghahary, A., Tredget, E. E., & Shen, Q. “. (1999) · Journal of Cellular Physiology · doi:10.1002/(sici)1097-4652(199907)180:1<61::aid-jcp7>3.0.co;2-r · Cited by 27
Metadata
- Authors
- MacDonald, R. G., Pfeffer, S. R., Coussens, L., Tepper, M. A., Brocklebank, C. M., Mole, J. E., Anderson, J. K., Chen, E., Czech, M. P., & Ullrich, A.
- Venue
- Science
- Published
- 1988-03-04
- Volume
- 239
- Issue
- 4844
- Pages
- 1134-1137
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2031997272
- Cited by
- 370
- References
- 2
- FWCI
- 36.82
- Type
- journal article
- Language
- en
- Open access
- closed
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- MacDonald, R. G., Pfeffer, S. R., Coussens, L., Tepper, M. A., Brocklebank, C. M., Mole, J. E., Anderson, J. K., Chen, E., Czech, M. P., & Ullrich, A. (1988). A Single Receptor Binds Both Insulin-Like Growth Factor II and Mannose-6-Phosphate. Science. https://doi.org/10.1126/science.2964083
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