The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Oxidative Autoactivation of Latent Collagenase by Human Neutrophils
Abstract
The pathological destruction of collagen plays a key role in the development of inflammatory disease states affecting every organ system in the human body. Neutrophils localized at inflammatory sites can potentially degrade collagen by releasing a metalloenzyme, collagenase, which is stored in a latent inactive form. Triggered human neutrophils were shown to release and simultaneously activate their latent collagenase. The activation of the latent enzyme was coupled to an oxidative process that required the generation of a highly reactive oxygen metabolite, hypochlorous acid. Oxidative regulation of latent collagenase activity may be important in the pathogenesis of connective tissue damage in vivo.
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Cites
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Structurally Distinct Collagen Types
Bornstein, P., & Sage, H. (1980) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.49.070180.004521 · Cited by 1,063
Chlorination of Taurine by Human Neutrophils
Weiss, S. J., Klein, R., Slivka, A., & Wei, M. (1982) · Journal of Clinical Investigation · doi:10.1172/jci110652 · Cited by 805
Self-citationGrisham, M. B., Jefferson, M. M., Melton, D. F., & Thomas, E. L. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)90979-8 · Cited by 395
Long-Lived Oxidants Generated by Human Neutrophils: Characterization and Bioactivity
Weiss, S. J., Lampert, M. B., & Test, S. T. (1983) · Science · doi:10.1126/science.6635660 · Cited by 388
Self-citationLazarus, G. S., Brown, R. S., Daniels, J. R., & Fullmer, H. M. (1968) · Science · doi:10.1126/science.159.3822.1483 · Cited by 327
Test, S. T., & Weiss, S. J. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)43674-x · Cited by 260
Self-citationWeiss, S. J., & Regiani, S. (1984) · Journal of Clinical Investigation · doi:10.1172/jci111332 · Cited by 247
Self-citationCawston, T. E., & Murphy, G. (1981) · Methods in Enzymology · doi:10.1016/s0076-6879(81)80054-7 · Cited by 219
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Cited by
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
Kessenbrock, K., Plaks, V., & Werb, Z. (2010) · Cell · doi:10.1016/j.cell.2010.03.015 · Cited by 5,151
Tissue Destruction by Neutrophils
Epstein, F. H., & Weiss, S. J. (1989) · New England Journal of Medicine · doi:10.1056/nejm198902093200606 · Cited by 3,950
Self-citationRole of Oxidative Modifications in Atherosclerosis
Stocker, R., & Keaney, J. F. (2004) · Physiological Reviews · doi:10.1152/physrev.00047.2003 · Cited by 2,624
Matrix metalloproteinases as modulators of inflammation and innate immunity
Parks, W. C., Wilson, C. L., & López-Boado, Y. S. (2004) · Nature Reviews Immunology · doi:10.1038/nri1418 · Cited by 1,929
Granules of the Human Neutrophilic Polymorphonuclear Leukocyte
Borregaard, N., & Cowland, J. B. (1997) · Blood · doi:10.1182/blood.v89.10.3503 · Cited by 1,522
Metadata
- Authors
- Weiss, S. J., Peppin, G., Ortiz, X., Ragsdale, C., & Test, S. T.
- Venue
- Science
- Published
- 1985-02-15
- Volume
- 227
- Issue
- 4688
- Pages
- 747-749
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2050536724
- Cited by
- 472
- References
- 16
- FWCI
- 10.88
- Type
- journal article
- Language
- en
- Open access
- closed
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- Weiss, S. J., Peppin, G., Ortiz, X., Ragsdale, C., & Test, S. T. (1985). Oxidative Autoactivation of Latent Collagenase by Human Neutrophils. Science. https://doi.org/10.1126/science.2982211
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
