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Cited by 996

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The Granulocyte-Macrophage Colony-Stimulating Factors

Metcalf, Donald·1985·Science

Abstract

The granulocyte-macrophage colony-stimulating factors are well-characterized specific glycoproteins that interact to control the production, differentiation, and function of two related white cell populations of the blood, the granulocytes and monocyte-macrophages. Widely produced in the body, these regulators probably play an important role in resistance to infections. The proliferation of myeloid leukemia cells remains dependent on stimulation by colony-stimulating factors, although one of them also has the ability to suppress leukemic populations by inducing terminal differentiation.

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Metadata

Authors
Metcalf, D.
Venue
Science
Published
1985-07-05
Volume
229
Issue
4708
Pages
16-22
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2036631709
Cited by
996
References
0
FWCI
42.02
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Granulocyte-Macrophage Colony-Stimulating Factors. https://app.cochat.ai/papers/10.1126/science.2990035
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Metcalf, D. (1985). The Granulocyte-Macrophage Colony-Stimulating Factors. Science. https://doi.org/10.1126/science.2990035

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.