The DOI matches its Crossref record.
Limitation of Excessive Myelopoiesis by the Intrinsic Modulation of Macrophage-Derived Prostaglandin E
Abstract
The clonal proliferation of the committed granulocyte-macrophage stem cell is controlled by a balance between mutually opposing factors, colony stimulating factor and prostaglandin E, both of monocyte-macrophage derivation. Increases beyond a critical concentration of colony stimulating factor within the local milieu of the mononuclear phagocyte induces the coincident elaboration of prostaglandin E, a self-regulated response which serves to limit the unopposed humoral stimulation of myelopoiesis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Prostaglandin E production by human blood monocytes and mouse peritoneal macrophages.
Kurland, J. I., & Bockman, R. (1978) · The Journal of experimental medicine · doi:10.1084/jem.147.3.952 · Cited by 482
Self-citationMacrophage activation, chronic inflammation and gastrointestinal disease
Tanner, A. R., Arthur, M. J., & Wright, R. (1984) · Gut · doi:10.1136/gut.25.7.760 · Cited by 70
Metadata
- Authors
- Kurland, J. I., Bockman, R. S., Broxmeyer, H. E., & Moore, M. A. S.
- Venue
- Science
- Published
- 1978-02-03
- Volume
- 199
- Issue
- 4328
- Pages
- 552-555
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2069978012
- Cited by
- 258
- References
- 0
- FWCI
- 31.51
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Limitation of Excessive Myelopoiesis by the Intrinsic Modulation of Macrophage-Derived Prostaglandin E. https://app.cochat.ai/papers/10.1126/science.304600
- The paper
- Kurland, J. I., Bockman, R. S., Broxmeyer, H. E., & Moore, M. A. S. (1978). Limitation of Excessive Myelopoiesis by the Intrinsic Modulation of Macrophage-Derived Prostaglandin E. Science. https://doi.org/10.1126/science.304600
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
