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Cited by 268

The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.

Phylogenetic Relations of Humans and African Apes from DNA Sequences in the ψη-Globin Region

Miyamoto, Michael M., Slightom, Jerry L., Goodman, Morris·1987·Science

Abstract

Sequences from the upstream and downstream flanking DNA regions of the ψη-globin locus in Pan troglodytes (common chimpanzee), Gorilla gorilla (gorilla), and Pongo pygmaeus (orangutan, the closest living relative to Homo , Pan , and Gorilla ) provided further data for evaluating the phylogenetic relations of humans and African apes. These newly sequenced orthologs [an additional 4.9 kilobase pairs (kbp) for each species] were combined with published ψη-gene sequences and then compared to the same orthologous stretch (a continuous 7.1-kbp region) available for humans. Phylogenetic analysis of these nucleotide sequences by the parsimony method indicated (i) that human and chimpanzee are more closely related to each other than either is to gorilla and (ii) that the slowdown in the rate of sequence evolution evident in higher primates is especially pronounced in humans. These results indicate that features (for example, knuckle-walking) unique to African apes (but not to humans) are primitive and that even local molecular clocks should be applied with caution.

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Metadata

Authors
Miyamoto, M. M., Slightom, J. L., & Goodman, M.
Venue
Science
Published
1987-10-16
Volume
238
Issue
4825
Pages
369-373
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W1964858855
Cited by
268
References
31
FWCI
46.63
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Phylogenetic Relations of Humans and African Apes from DNA Sequences in the ψη-Globin Region. https://app.cochat.ai/papers/10.1126/science.3116671
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Miyamoto, M. M., Slightom, J. L., & Goodman, M. (1987). Phylogenetic Relations of Humans and African Apes from DNA Sequences in the ψη-Globin Region. Science. https://doi.org/10.1126/science.3116671

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