The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Endorphins: Naloxone Fails to Alter Experimental Pain or Mood in Humans
Abstract
In 30 human subjects, experimental pain was produced by either ischemia or cold-water immersion. In a double-blind procedure, intravenous doses of up to 10 milligrams of naloxone hydrochloride in saline were indistinguishable from similarly administered saline alone. There were no effects on subjective pain ratings, finger plethysmograph recordings, or responses to mood-state questionnaires. These laboratory procedures do not activate any functionally significant pain-attenuating or mood-altering effect of endorphins.
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Citations
Cites
Identification of two related pentapeptides from the brain with potent opiate agonist activity
Hughes, J., Smith, T. W., Kosterlitz, H. W., Fothergill, L. A., Morgan, B. A., & Morris, H. R. (1975) · Nature · doi:10.1038/258577a0 · Cited by 3,806
Cited by
The opponent-process theory of acquired motivation: the costs of pleasure and the benefits of pain
Solomon, R. L. (1980) · American Psychologist · doi:10.1037/0003-066x.35.8.691 · Cited by 1,194
The neurobiology and control of anxious states
Millan, M. J. (2003) · Progress in Neurobiology · doi:10.1016/s0301-0082(03)00087-x · Cited by 965
Amanzio, M., & Benedetti, F. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-01-00484.1999 · Cited by 899
Activation of the Opioidergic Descending Pain Control System Underlies Placebo Analgesia
Eippert, F., Bingel, U., Schoell, E. D., Yacubian, J., Klinger, R., Lorenz, J., & Büchel, C. (2009) · Neuron · doi:10.1016/j.neuron.2009.07.014 · Cited by 839
Organization of endogenous opiate and nonopiate pain control systems
Watkins, L. R., & Mayer, D. J. (1982) · Science · doi:10.1126/science.6281891 · Cited by 791
Metadata
- Authors
- Grevert, P., & Goldstein, A.
- Venue
- Science
- Published
- 1978-03-10
- Volume
- 199
- Issue
- 4333
- Pages
- 1093-1095
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2049153510
- Cited by
- 186
- References
- 1
- FWCI
- 6.49
- Type
- journal article
- Language
- en
- Open access
- closed
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- Grevert, P., & Goldstein, A. (1978). Endorphins: Naloxone Fails to Alter Experimental Pain or Mood in Humans. Science. https://doi.org/10.1126/science.343250
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
