The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Models for the Specific Adhesion of Cells to Cells: A theoretical framework for adhesion mediated by reversible bonds between cell surface molecules.
Abstract
A theoretical framework is proposed for the analysis of adhesion between cells or of cells to surfaces when the adhesion is mediated by reversible bonds between specific molecules such as antigen and antibody, lectin and carbohydrate, or enzyme and substrate. From a knowledge of the reaction rates for reactants in solution and of their diffusion constants both in solution and on membranes, it is possible to estimate reaction rates for membrane-bound reactants. Two models are developed for predicting the rate of bond formation between cells and are compared with experiments. The force required to separate two cells is shown to be greater than the expected electrical forces between cells, and of the same order of magnitude as the forces required to pull gangliosides and perhaps some integral membrane proteins out of the cell membrane.
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Citations
Cites
Measurement of forces between lecithin bilayers
LENEVEU, D. M., RAND, R. P., & PARSEGIAN, V. A. (1976) · Nature · doi:10.1038/259601a0 · Cited by 563
Cited by
Noncovalent interactions: A challenge for experiment and theory
Müller-Dethlefs, K., & Hobza, P. (2000) · Chemical Reviews · doi:10.1021/cr9900331 · Cited by 1,781
Beachey, E. H. (1981) · Journal of Infectious Diseases · doi:10.1093/infdis/143.3.325 · Cited by 1,411
Integrins as biomechanical sensors of the microenvironment
Kechagia, J. Z., Ivaska, J., & Roca-Cusachs, P. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0134-2 · Cited by 1,311
INTERACTIONS BETWEEN NEUTRAL PHOSPHOLIPID BILAYER MEMBRANES
LIS, L. J., MCALISTER, M., FULLER, N., RAND, R. P., & PARSEGIAN, V. A. (1982) · Biophysical Journal · doi:10.1016/s0006-3495(21)00385-4 · Cited by 758
Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor
Yang, J., Petitjean, S. J. L., Koehler, M., Zhang, Q., Dumitru, A. C., Chen, W., Derclaye, S., Vincent, S. P., Soumillion, P., & Alsteens, D. (2020) · Nature Communications · doi:10.1038/s41467-020-18319-6 · Cited by 615
Metadata
- Authors
- Bell, G. I.
- Venue
- Science
- Published
- 1978-05-12
- Volume
- 200
- Issue
- 4342
- Pages
- 618-627
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2052192720
- Cited by
- 4,328
- References
- 1
- FWCI
- 7.84
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bell, G. I. (1978). Models for the Specific Adhesion of Cells to Cells: A theoretical framework for adhesion mediated by reversible bonds between cell surface molecules. Science. https://doi.org/10.1126/science.347575
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.