The DOI matches its Crossref record.
A Plant Flavone, Luteolin, Induces Expression of Rhizobium meliloti Nodulation Genes
Abstract
The symbiotic interaction of Rhizobium meliloti and alfalfa results in the formation of nitrogen-fixing root nodules. Rhizobium meliloti nodABC genes are required for the early host responses of cortical cell divisions and root hair curling. The induction of nodABC expression by alfalfa exudates demonstrates host-symbiont signaling at an early stage in nodule development. The inducer molecule for nodABC expression was isolated from plant exudate by constructing a nodABC - lacZ fusion to monitor the inducing activity. From ultraviolet-visible absorption spectra, proton nuclear magnetic resonance, and mass spectrometry, the inducer was determined to be 3′,4′,5,7-tetrahydroxyflavone (luteolin). Luteolin is a normal secondary plant metabolite found throughout the plant kingdom that may serve to control nodABC expression during nodule development. This regulatory role for a flavone contrasts with the function of some flavonoids as defense compounds.
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Cited by
Middleton, E., Kandaswami, C., & Theoharides, T. C. (2000) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01472-8 · Cited by 4,882
THE ROLE OF ROOT EXUDATES IN RHIZOSPHERE INTERACTIONS WITH PLANTS AND OTHER ORGANISMS
Bais, H. P., Weir, T. L., Perry, L. G., Gilroy, S., & Vivanco, J. M. (2006) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.57.032905.105159 · Cited by 4,682
Distribution and biological activities of the flavonoid luteolin
Lopez-Lazaro, M. (2009) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/138955709787001712 · Cited by 1,106
Environmental Signaling: What Embryos and Evolution Teach Us About Endocrine Disrupting Chemicals
McLachlan, J. A. (2001) · Endocrine Reviews · doi:10.1210/edrv.22.3.0432 · Cited by 608
Moran, J. F., Klucas, R. V., Grayer, R. J., Abian, J., & Becana, M. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00426-1 · Cited by 369
Metadata
- Authors
- Peters, N. K., Frost, J. W., & Long, S. R.
- Venue
- Science
- Published
- 1986-08-29
- Volume
- 233
- Issue
- 4767
- Pages
- 977-980
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2076248870
- Cited by
- 972
- References
- 0
- FWCI
- 71.27
- Type
- journal article
- Language
- en
- Open access
- closed
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- Peters, N. K., Frost, J. W., & Long, S. R. (1986). A Plant Flavone, Luteolin, Induces Expression of Rhizobium meliloti Nodulation Genes. Science. https://doi.org/10.1126/science.3738520
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