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Cited by 636

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Neuroleptic-Induced "Anhedonia" in Rats: Pimozide Blocks Reward Quality of Food

Wise, Roy A., Spindler, Joan, deWit, Harriet, Gerberg, Gary J.·1978·Science

Abstract

The dopamine receptor blocker pimozide attenuated lever-pressing and running for food reward in hungry rats. In each case the characteristic behavior of pimozide-treated rats was the same as that of undrugged rats when reward was simply withheld. Drug-induced performance difficulties were ruled out by the presence of periods of normal responding in drug-treated animals. Pimozide appears to selectively blunt the rewarding impact of food and other hedonic stimuli.

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Crossref · 10.1126/science.566469

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Metadata

Authors
Wise, R. A., Spindler, J., deWit, H., & Gerberg, G. J.
Venue
Science
Published
1978-07-21
Volume
201
Issue
4352
Pages
262-264
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2046837952
Cited by
636
References
1
FWCI
4.15
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Neuroleptic-Induced "Anhedonia" in Rats: Pimozide Blocks Reward Quality of Food. https://app.cochat.ai/papers/10.1126/science.566469
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Wise, R. A., Spindler, J., deWit, H., & Gerberg, G. J. (1978). Neuroleptic-Induced "Anhedonia" in Rats: Pimozide Blocks Reward Quality of Food. Science. https://doi.org/10.1126/science.566469

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.