The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
HTLV-III in Saliva of People with AIDS-Related Complex and Healthy Homosexual Men at Risk for AIDS
Abstract
Peripheral blood leukocytes and saliva from 20 individuals, including four with the acquired immune deficiency syndrome (AIDS), ten with AIDS-related complex (ARC), and six healthy homosexual males at risk for AIDS, were compared as sources of transmissible human T-cell leukemia (lymphotropic) virus type III (HTLV-III), the virus found to be the etiologic agent of AIDS. All of the AIDS and ARC patients and four of the six healthy homosexuals had evidence of prior exposure to HTLV-III as indicated by seropositivity for antibody to HTLV-III structural proteins. Infectious virus was isolated from the peripheral blood of one of the AIDS patients, four of the ARC patients, and two of the healthy homosexual males, consistent with previous reports. HTLV-III was also isolated from the saliva of four of the ARC patients and four of the healthy homosexuals. Virus was also observed by electron microscopy in material prepared by centrifugation of the saliva of one AIDS patient. Although AIDS does not appear to be transmitted by casual contact, the possibility that HTLV-III can be transmitted by saliva should be considered.
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Citations
Cites
Acquired Immunodeficiency Syndrome in African Patients
Clumeck, N., Sonnet, J., Taelman, H., Mascart-Lemone, F., De Bruyere, M., Vandeperre, P., Dasnoy, J., Marcelis, L., Lamy, M., Jonas, C., et al. (1984) · New England Journal of Medicine · doi:10.1056/nejm198402233100804 · Cited by 301
Cited by
Complete nucleotide sequence of the AIDS virus, HTLV-III
Ratner, L., Haseltine, W., Patarca, R., Livak, K. J., Starcich, B., Josephs, S. F., Doran, E. R., Rafalski, J. A., Whitehorn, E. A., Baumeister, K., et al. (1985) · Nature · doi:10.1038/313277a0 · Cited by 2,245
Self-citationPathogenesis of lentivirus infections
Haase, A. T. (1986) · Nature · doi:10.1038/322130a0 · Cited by 566
Characterization of gp41 as the Transmembrane Protein Coded by the HTLV-III/LAV Envelope Gene
Veronese, F. D., DeVico, A. L., Copeland, T. D., Oroszlan, S., Gallo, R. C., & Sarngadharan, M. G. (1985) · Science · doi:10.1126/science.2994223 · Cited by 437
Self-citationSequence Homology and Morphologic Similarity of HTLV-III and Visna Virus, a Pathogenic Lentivirus
Gonda, M. A., Wong-Staal, F., Gallo, R. C., Clements, J. E., Narayan, O., & Gilden, R. V. (1985) · Science · doi:10.1126/science.2981428 · Cited by 405
Self-citationEvaluation of Heterosexual Partners, Children, and Household Contacts of Adults With AIDS
Fischl, M. A. (1987) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1987.03390050066020 · Cited by 379
Metadata
- Authors
- Groopman, J. E., Salahuddin, S. Z., Sarngadharan, M. G., Markham, P. D., Gonda, M., Sliski, A., & Gallo, R. C.
- Venue
- Science
- Published
- 1984-10-26
- Volume
- 226
- Issue
- 4673
- Pages
- 447-449
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2059005571
- Cited by
- 363
- References
- 1
- FWCI
- 11.05
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: HTLV-III in Saliva of People with AIDS-Related Complex and Healthy Homosexual Men at Risk for AIDS. https://app.cochat.ai/papers/10.1126/science.6093247
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- Groopman, J. E., Salahuddin, S. Z., Sarngadharan, M. G., Markham, P. D., Gonda, M., Sliski, A., & Gallo, R. C. (1984). HTLV-III in Saliva of People with AIDS-Related Complex and Healthy Homosexual Men at Risk for AIDS. Science. https://doi.org/10.1126/science.6093247
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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