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Evidence for L-glutamate as the Neurotransmitter of Baroreceptor Afferent Nerve Fibers
Abstract
Microinjection of L-glutamate into the intermediate nucleus tractus solitarii in anesthetized rats elicits hypotension, bradycardia, and apnea, simulating baroreceptor reflexes. Ablation of the nodose ganglion results in selective reduction of high-affinity uptake of L-glutanate in the nucleus tractus solitarii. L-Glutamate may be the neurotransmitter of afferent nerve fibers from arterial baroreceptors.
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Cited by
Amino acid neurotransmitters and their pathways in the mammalian central nervous system
Fagg, G. E., & Foster, A. C. (1983) · Neuroscience · doi:10.1016/0306-4522(83)90263-4 · Cited by 649
Chapter 4 Cell death in models of spinal cord injury
Beattie, M. S., Hermann, G. E., Rogers, R. C., & Bresnahan, J. C. (2002) · Progress in Brain Research · doi:10.1016/s0079-6123(02)37006-7 · Cited by 453
Harada, S., Tokunaga, S., Momohara, M., Masaki, H., Tagawa, T., Imaizumi, T., & Takeshita, A. (1993) · Circulation Research · doi:10.1161/01.res.72.3.511 · Cited by 275
Vasopressor and depressor areas in the rat medulla
Willette, R. N., Barcas, P. P., Krieger, A. J., & Sapru, H. N. (1983) · Neuropharmacology · doi:10.1016/0028-3908(83)90027-8 · Cited by 268
Leslie, R. A. (1985) · Neurochemistry International · doi:10.1016/0197-0186(85)90106-8 · Cited by 174
Metadata
- Authors
- Talman, W. T., Perrone, M. H., & Reis, D. J.
- Venue
- Science
- Published
- 1980-08-15
- Volume
- 209
- Issue
- 4458
- Pages
- 813-815
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2022332003
- Cited by
- 452
- References
- 0
- FWCI
- 11.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Evidence for L-glutamate as the Neurotransmitter of Baroreceptor Afferent Nerve Fibers. https://app.cochat.ai/papers/10.1126/science.6105709
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- Talman, W. T., Perrone, M. H., & Reis, D. J. (1980). Evidence for L-glutamate as the Neurotransmitter of Baroreceptor Afferent Nerve Fibers. Science. https://doi.org/10.1126/science.6105709
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.