The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Caffeine and Related Methylxanthines: Possible Naturally Occurring Pesticides
Abstract
Natural and synthetic methylxanthines inhibit insect feeding and are pesticidal at concentrations known to occur in plants. These effects are due primarily to inhibition of phosphodiesterase activity and to an increase in intracellular cyclic adenosine monophosphate. At lower concentrations, methylxanthines are potent synergists of other pesticides known to activate adenylate cyclase in insects. These data suggest that methylxanthines may function as natural insecticides and that phosphodiesterase inhibitors, alone or in combination with other compounds, may be useful in insect control.
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Citations
Cites
Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells.
Seamon, K. B., Padgett, W., & Daly, J. W. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.6.3363 · Cited by 1,658
Cited by
Plant Defense Against Herbivores: Chemical Aspects
Mithöfer, A., & Boland, W. (2012) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042110-103854 · Cited by 1,610
Gut microbiota mediate caffeine detoxification in the primary insect pest of coffee
Ceja-Navarro, J. A., Vega, F. E., Karaoz, U., Hao, Z., Jenkins, S., Lim, H. C., Kosina, P., Infante, F., Northen, T. R., & Brodie, E. L. (2015) · Nature Communications · doi:10.1038/ncomms8618 · Cited by 512
Caffeine and Related Purine Alkaloids: Biosynthesis, Catabolism, Function and Genetic Engineering
Ashihara, H., Sano, H., & Crozier, A. (2008) · Phytochemistry · doi:10.1016/j.phytochem.2007.10.029 · Cited by 430
Caffeine as a repellent for slugs and snails
Hollingsworth, R. G., Armstrong, J. W., & Campbell, E. (2002) · Nature · doi:10.1038/417915a · Cited by 165
Nylund, G. M., Weinberger, F., Rempt, M., & Pohnert, G. (2011) · PLoS ONE · doi:10.1371/journal.pone.0029359 · Cited by 117
“In many cases, chemical ecologists have shown defence roles of previously described plant metabolites by testing their effect on palatability and grazer performance”
Background
Metadata
- Authors
- Nathanson, J. A.
- Venue
- Science
- Published
- 1984-10-12
- Volume
- 226
- Issue
- 4671
- Pages
- 184-187
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2007342471
- Cited by
- 325
- References
- 1
- FWCI
- 10.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Caffeine and Related Methylxanthines: Possible Naturally Occurring Pesticides. https://app.cochat.ai/papers/10.1126/science.6207592
- The paper
- Nathanson, J. A. (1984). Caffeine and Related Methylxanthines: Possible Naturally Occurring Pesticides. Science. https://doi.org/10.1126/science.6207592
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
