The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Pro-Adrenocorticotropin/Endorphin-Derived Peptides: Coordinate Action on Adrenal Steroidogenesis
Abstract
A synthetic peptide, representing a portion of the 16K (16,000 dalton)-fragment sequence within the pro-adrenocorticotropin/endorphin precursor molecule, potentiates the steroidogenic action of the 1 to 24 portion of adrenocorticotropin [ACTH(1-24)] on the rat adrenal cortex. The peptide has 27 amino acid residues and consists of γ-melanotropin with a carboxyl terminal extension. It affects both the inner and outer adrenocortical zones of hypophysectomized animals, as evidenced by a synergistic augmentation of corticosterone and aldosterone production, respectively. The peptide can be distinguished from adrenocorticotropin by its activation of cholesterol ester hydrolase and its failure to stimulate cholesterol side-chain cleavage.
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Citations
Cites
β-Endorphin and Adrenocorticotropin Are Selected Concomitantly by the Pituitary Gland
Guillemin, R., Vargo, T., Rossier, J., Minick, S., Ling, N., Rivier, C., Vale, W., & Bloom, F. (1977) · Science · doi:10.1126/science.197601 · Cited by 1,419
Self-citation
Cited by
Molecular biology of steroid hormone synthesis
MILLER, W. L. (1988) · Endocrine Reviews · doi:10.1210/edrv-9-3-295 · Cited by 1,397
Neuroendocrine Control of Body Fluid Metabolism
ANTUNES-RODRIGUES, J., DE CASTRO, M., ELIAS, L. L. K., VALENÇA, M. M., & McCANN, S. M. (2004) · Physiological Reviews · doi:10.1152/physrev.00017.2003 · Cited by 468
Atkinson, H. C., & Waddell, B. J. (1997) · Endocrinology · doi:10.1210/endo.138.9.5395 · Cited by 438
DE SOUZA, E. B., & VAN LOON, G. R. (1982) · Endocrinology · doi:10.1210/endo-110-1-23 · Cited by 113
Regulation of ACTH-induced steroidogenesis in human fetal adrenals by rTNF-α
Jäättelä, M., Carpén, O., Stenman, U.-H., & Saksela, E. (1990) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(90)90196-f · Cited by 54
Metadata
- Authors
- Pedersen, R. C., Brownie, A. C., & Ling, N.
- Venue
- Science
- Published
- 1980-05-30
- Volume
- 208
- Issue
- 4447
- Pages
- 1044-1046
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2053245866
- Cited by
- 198
- References
- 1
- FWCI
- 25.92
- Type
- journal article
- Language
- en
- Open access
- closed
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- Pedersen, R. C., Brownie, A. C., & Ling, N. (1980). Pro-Adrenocorticotropin/Endorphin-Derived Peptides: Coordinate Action on Adrenal Steroidogenesis. Science. https://doi.org/10.1126/science.6246578
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
