The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
2-Amino-4-Phosphonobutyric Acid: A New Pharmacological Tool for Retina Research
Abstract
Information processing in the vertebrate retina occurs in two separate channels known as ON and OFF channels. When intracellular electrophysiological recordings were obtained from the perfused retina-eyecup preparation of the mudpuppy (Necturus maculosus), the addition of 2-amino-4-phosphonobutyric acid to the bathing medium blocked all responses in the ON channel but left intact the OFF responses including OFF ganglion cell discharge. 2-Amino-4-phosphonobutyric acid blocks the light response of the ON bipolar cell by mimicking the endogenous photoreceptor transmitter.
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Citations
Cites
Receptive fields, binocular interaction and functional architecture in the cat’s visual cortex
Hubel, D. H., & Wiesel, T. N. (1962) · The Journal of Physiology · doi:10.1113/jphysiol.1962.sp006837 · Cited by 13,680
Cited by
Design Principles of Insect and Vertebrate Visual Systems
Sanes, J. R., & Zipursky, S. L. (2010) · Neuron · doi:10.1016/j.neuron.2010.01.018 · Cited by 561
Anatomical distributions of four pharmacologically distinct 3H-L-glutamate binding sites
Monaghan, D. T., Holets, V. R., Toy, D. W., & Cotman, C. W. (1983) · Nature · doi:10.1038/306176a0 · Cited by 522
B-wave of the electroretinogram. A reflection of ON bipolar cell activity
Stockton, R. A., & Slaughter, M. M. (1989) · The Journal of general physiology · doi:10.1085/jgp.93.1.101 · Cited by 446
Self-citationRod Vision: Pathways and Processing in the Mammalian Retina
Bloomfield, S. A., & Dacheux, R. F. (2001) · Progress in Retinal and Eye Research · doi:10.1016/s1350-9462(00)00031-8 · Cited by 375
Dopamine enhances excitatory amino acid-gated conductances in cultured retinal horizontal cells
Knapp, A. G., & Dowling, J. E. (1987) · Nature · doi:10.1038/325437a0 · Cited by 286
Metadata
- Authors
- Slaughter, M. M., & Miller, R. F.
- Venue
- Science
- Published
- 1981-01-09
- Volume
- 211
- Issue
- 4478
- Pages
- 182-185
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2072060769
- Cited by
- 820
- References
- 1
- FWCI
- 8.07
- Type
- journal article
- Language
- en
- Open access
- closed
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- Slaughter, M. M., & Miller, R. F. (1981). 2-Amino-4-Phosphonobutyric Acid: A New Pharmacological Tool for Retina Research. Science. https://doi.org/10.1126/science.6255566
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
