The DOI matches its Crossref record.
Receptor for Albumin on the Liver Cell Surface May Mediate Uptake of Fatty Acids and Other Albumin-Bound Substances
Abstract
Kinetic analysis of the uptake of carbon-14-labeled oleate in a single-pass perfusion of rat liver and saturable and specific binding of iodine-125-labeled albumin to hepatocytes in suspension suggest the existence of a receptor for albumin on the liver cell surface. The putative receptor appears to mediate uptake of albumin-bound fatty acids by the cell and may account for the efficient hepatic extraction of many other substances tightly bound to albumin.
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Citations
Cited by
Greenblatt (1982) · doi:10.1056/nejm198205063061804 · Cited by 584
Macromolecular permeability across the blood-nerve and blood-brain barriers.
Poduslo, J. F., Curran, G. L., & Berg, C. T. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.12.5705 · Cited by 377
Ghitescu, L., Fixman, A., Simionescu, M., & Simionescu, N. (1986) · The Journal of cell biology · doi:10.1083/jcb.102.4.1304 · Cited by 369
Albumin Binding and Hepatic Uptake: The Importance of Model Selection
Forker, E. L., & Luxon, B. A. (1983) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600721038 · Cited by 22
Metadata
- Authors
- Weisiger, R., Gollan, J., & Ockner, R.
- Venue
- Science
- Published
- 1981-03-06
- Volume
- 211
- Issue
- 4486
- Pages
- 1048-1051
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2059656737
- Cited by
- 382
- References
- 0
- FWCI
- 12.02
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Receptor for Albumin on the Liver Cell Surface May Mediate Uptake of Fatty Acids and Other Albumin-Bound Substances. https://app.cochat.ai/papers/10.1126/science.6258226
- The paper
- Weisiger, R., Gollan, J., & Ockner, R. (1981). Receptor for Albumin on the Liver Cell Surface May Mediate Uptake of Fatty Acids and Other Albumin-Bound Substances. Science. https://doi.org/10.1126/science.6258226
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
