The DOI matches its Crossref record.
High Levels of Intracellular Bombesin Characterize Human Small-Cell Lung Carcinoma
Abstract
"Small cells" or "oat cells" characterize a virulent form of lung cancer and share many biochemical properties with peptide-secreting neurones. The neuropeptide bombesin is present in all small-cell lines examined, but not in other lung cancer cell lines, suggesting that bombesinergic precursor cells in lung may give rise to this disease.
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Citations
Cited by
Autocrine growth factors and cancer
Sporn, M. B., & Roberts, A. B. (1985) · Nature · doi:10.1038/313745a0 · Cited by 1,438
Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells.
Rozengurt, E., & Sinnett-Smith, J. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.10.2936 · Cited by 464
Oxygen sensing in airway chemoreceptors
Youngson, C., Nurse, C., Yeger, H., & Cutz, E. (1993) · Nature · doi:10.1038/365153a0 · Cited by 458
Morley, J. E., & Silver, A. J. (1988) · Neurobiology of Aging · doi:10.1016/s0197-4580(88)80004-6 · Cited by 386
Neuroendocrine differentiation in prostatic carcinoma
Abrahamsson, P.-A. (1999) · The Prostate · doi:10.1002/(sici)1097-0045(19990501)39:2<135::aid-pros9>3.0.co;2-s · Cited by 370
Metadata
- Authors
- Moody, T. W., Pert, C. B., Gazdar, A. F., Carney, D. N., & Minna, J. D.
- Venue
- Science
- Published
- 1981-12-11
- Volume
- 214
- Issue
- 4526
- Pages
- 1246-1248
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2043073430
- Cited by
- 487
- References
- 0
- FWCI
- 10.95
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: High Levels of Intracellular Bombesin Characterize Human Small-Cell Lung Carcinoma. https://app.cochat.ai/papers/10.1126/science.6272398
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- Moody, T. W., Pert, C. B., Gazdar, A. F., Carney, D. N., & Minna, J. D. (1981). High Levels of Intracellular Bombesin Characterize Human Small-Cell Lung Carcinoma. Science. https://doi.org/10.1126/science.6272398
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.