The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Evolution of Proteolytic Enzymes
Abstract
Proteolytic enzymes have many physiological functions, ranging from generalized protein digestion to more specific regulated processes such as the activation of zymogens, blood coagulation and the lysis of fibrin clots, the release of hormones and pharmacologically active peptides from precursor proteins, and the transport of secretory proteins across membranes. They are present in all forms of living organisms. Comparisons of amino acid sequences, three-dimensional structures, and enzymatic reaction mechanisms of proteases indicate that there are distinct families of these proteins. Changes in molecular structure and function have accompanied the evolution of proteolytic enzymes and their inhibitors, each having relatively simple roles in primitive organisms and more diverse and more complex functions in higher organisms.
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Cites
Electrochemical Photolysis of Water at a Semiconductor Electrode
FUJISHIMA, A., & HONDA, K. (1972) · Nature · doi:10.1038/238037a0 · Cited by 34,169
Selforganization of matter and the evolution of biological macromolecules
Eigen, M. (1971) · Die Naturwissenschaften · doi:10.1007/bf00623322 · Cited by 3,788
Gilbert, W. (1978) · Nature · doi:10.1038/271501a0 · Cited by 2,300
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Falivene, L., Cao, Z., Petta, A., Serra, L., Poater, A., Oliva, R., Scarano, V., & Cavallo, L. (2019) · Nature Chemistry · doi:10.1038/s41557-019-0319-5 · Cited by 1,290
Autocatalytic sets of proteins
Kauffman, S. A. (1986) · Journal of Theoretical Biology · doi:10.1016/s0022-5193(86)80047-9 · Cited by 741
Luminescent Gold Nanoparticles with Efficient Renal Clearance
Zhou, C., Long, M., Qin, Y., Sun, X., & Zheng, J. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201007321 · Cited by 490
Serial killers: ordering caspase activation events in apoptosis
Slee, E., Adrain, C., & Martin, S. (1999) · Cell Death & Differentiation · doi:10.1038/sj.cdd.4400601 · Cited by 473
Gorbalenya, A. E., Donchenko, A. P., Blinov, V. M., & Koonin, E. V. (1989) · FEBS Letters · doi:10.1016/0014-5793(89)80109-7 · Cited by 440
Metadata
- Authors
- Neurath, H.
- Venue
- Science
- Published
- 1984-04-27
- Volume
- 224
- Issue
- 4647
- Pages
- 350-357
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2070018377
- Cited by
- 644
- References
- 3
- FWCI
- 23.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- Neurath, H. (1984). Evolution of Proteolytic Enzymes. Science. https://doi.org/10.1126/science.6369538
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
