The DOI matches its Crossref record.
Anticarcinoma Activity in Vivo of Rhodamine 123, a Mitochondrial-Specific Dye
Abstract
Carcinoma cells and normal epithelial cells differ in the mitochondrial retention of a permeant cationic compound, rhodamine 123. The possibility of utilizing this difference in carcinoma chemotherapy was investigated. Rhodamine 123 exhibited anticarcinoma activity in mice, and this activity was potentiated by 2-deoxyglucose.
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Cited by
Zielonka, J., Joseph, J., Sikora, A., Hardy, M., Ouari, O., Vasquez-Vivar, J., Cheng, G., Lopez, M., & Kalyanaraman, B. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00042 · Cited by 1,683
Energy metabolism in tumor cells
Moreno‐Sánchez, R., Rodríguez‐Enríquez, S., Marín‐Hernández, A., & Saavedra, E. (2007) · The FEBS Journal · doi:10.1111/j.1742-4658.2007.05686.x · Cited by 1,082
Emaus, R. K., Grunwald, R., & Lemasters, J. J. (1986) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(86)90112-x · Cited by 800
PHOTOCHEMOTHERAPY OF CANCER: EXPERIMENTAL RESEARCH
Moan, J., & Berg, K. (1992) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1992.tb08541.x · Cited by 368
Anticancer Drugs Targeting the Mitochondrial Electron Transport Chain
Rohlena, J., Dong, L.-F., Ralph, S. J., & Neuzil, J. (2011) · Antioxidants & Redox Signaling · doi:10.1089/ars.2011.3990 · Cited by 91
Metadata
- Authors
- Bernal, S. D., Lampidis, T. J., McIsaac, R. M., & Chen, L. B.
- Venue
- Science
- Published
- 1983-10-14
- Volume
- 222
- Issue
- 4620
- Pages
- 169-172
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2049857745
- Cited by
- 220
- References
- 0
- FWCI
- 4.20
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Anticarcinoma Activity in Vivo of Rhodamine 123, a Mitochondrial-Specific Dye. https://app.cochat.ai/papers/10.1126/science.6623064
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- Bernal, S. D., Lampidis, T. J., McIsaac, R. M., & Chen, L. B. (1983). Anticarcinoma Activity in Vivo of Rhodamine 123, a Mitochondrial-Specific Dye. Science. https://doi.org/10.1126/science.6623064
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
