The DOI matches its Crossref record.
The Heart Is a Target Organ for Androgen
Abstract
Autoradiographic and biochemical analyses of the hearts of female rhesus monkeys and baboons indicate that atrial and ventricular myocardial cells contain androgen receptors. Although the specific effects of nuclear uptake and retention of androgen on the function of heart muscle cells are not known, the presence of this receptor suggests that sex steroid hormones may affect myocardial function directly and may explain some of the peculiar differences in heart disease between men and women.
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Citations
Cited by
The Decline of Androgen Levels in Elderly Men and Its Clinical and Therapeutic Implications
Kaufman, J. M., & Vermeulen, A. (2005) · Endocrine Reviews · doi:10.1210/er.2004-0013 · Cited by 1,079
Mechanistic Pathways of Sex Differences in Cardiovascular Disease
Regitz-Zagrosek, V., & Kararigas, G. (2017) · Physiological Reviews · doi:10.1152/physrev.00021.2015 · Cited by 732
Testosterone: A Major Determinant of Extragenital Sexual Dimorphism
Bardin, C. W., & Catterall, J. F. (1981) · Science · doi:10.1126/science.7010603 · Cited by 386
The cardiac toxicity of anabolic steroids
Sullivan, M. L., Martinez, C. M., Gennis, P., & Gallagher, E. J. (1998) · Progress in Cardiovascular Diseases · doi:10.1016/s0033-0620(98)80019-4 · Cited by 342
Turgeon, J. L., Carr, M. C., Maki, P. M., Mendelsohn, M. E., & Wise, P. M. (2006) · Endocrine Reviews · doi:10.1210/er.2005-0020 · Cited by 264
Metadata
- Authors
- McGill, H. C., Anselmo, V. C., Buchanan, J. M., & Sheridan, P. J.
- Venue
- Science
- Published
- 1980-02-15
- Volume
- 207
- Issue
- 4432
- Pages
- 775-777
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2006178846
- Cited by
- 159
- References
- 0
- FWCI
- 6.15
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The Heart Is a Target Organ for Androgen. https://app.cochat.ai/papers/10.1126/science.6766222
- The paper
- McGill, H. C., Anselmo, V. C., Buchanan, J. M., & Sheridan, P. J. (1980). The Heart Is a Target Organ for Androgen. Science. https://doi.org/10.1126/science.6766222
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
