The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Entry of Opioid Peptides into the Central Nervous System
Abstract
Cerebrovascular permeability of four modified opioid peptides—[D-Ala 2 ]methionine enkephalin amide, β-[D-Ala 62 , 14 C- Homoarg 69 ]lipotropin 61-69, α-[D-Ala 2 , 14 C-Homoarg 9 ]endorphin, and β-[D-Ala 2 , 14 C-Homoarg]endorphin—ranged from 1.4 to 3.9 × 10 -6 centimeters per second in brain regions of the conscious rat. These significant permeabilities should allow the peptides to fill the extracellular brain space with a half time of 3 to 11 minutes, as a result of a step increase in plasma concentration of unbound peptide.
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Cites
Sokoloff, L., Reivich, M., Kennedy, C., Rosiers, M. H. D., Patlak, C. S., Pettigrew, K. D., Sakurada, O., & Shinohara, M. (1977) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1977.tb10649.x · Cited by 6,000
Self-citationFINE STRUCTURAL LOCALIZATION OF A BLOOD-BRAIN BARRIER TO EXOGENOUS PEROXIDASE
Reese, T. S., & Karnovsky, M. J. (1967) · The Journal of Cell Biology · doi:10.1083/jcb.34.1.207 · Cited by 2,629
Cited by
The opiomelanotropinergic neuronal and endocrine systems
O'Donohue, T. L., & Dorsa, D. M. (1982) · Peptides · doi:10.1016/0196-9781(82)90098-5 · Cited by 536
Pomerlau (1984) · doi:10.1016/0149-7634(84)90007-1 · Cited by 378
Mens, W. B. J., Witter, A., & Van Wimersma Greidanus, T. B. (1983) · Brain Research · doi:10.1016/0006-8993(83)90478-x · Cited by 360
Peptides and the blood-brain barrier: Lipophilicity as a predictor of permeability
Banks, W. A., & Kastin, A. J. (1985) · Brain Research Bulletin · doi:10.1016/0361-9230(85)90153-4 · Cited by 306
Opioid peptides and primary biliary cirrhosis
Thornton, J. R., & Losowsky, M. S. (1988) · BMJ · doi:10.1136/bmj.297.6662.1501 · Cited by 300
Metadata
- Authors
- Rapoport, S. I., Klee, W. A., Pettigrew, K. D., & Ohno, K.
- Venue
- Science
- Published
- 1980-01-04
- Volume
- 207
- Issue
- 4426
- Pages
- 84-86
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1971232468
- Cited by
- 245
- References
- 2
- FWCI
- 28.27
- Type
- journal article
- Language
- en
- Open access
- closed
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- Rapoport, S. I., Klee, W. A., Pettigrew, K. D., & Ohno, K. (1980). Entry of Opioid Peptides into the Central Nervous System. Science. https://doi.org/10.1126/science.7350645
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
