The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Reduced Rate of Disease Development After HIV-2 Infection as Compared to HIV-1
Abstract
Human immunodeficiency virus type-2 (HIV-2) is a close relative of the prototype acquired immunodeficiency syndrome (AIDS) virus, HIV-1. HIV-2 is biologically similar to HIV-1, but information is lacking concerning clinical outcomes of HIV-2-infected individuals. From 1985 to 1993, a prospective clinical study was conducted in women with HIV-2 and HIV-1 infection to determine and compare rates of disease development. HIV-1-infected women had a 67% probability of AIDS-free survival 5 years after seroconversion in contrast with 100% for HIV-2-infected women. In addition to having significantly less HIV-related disease outcome in HIV-2 enrollees compared to HIV-1 enrollees, the rate of developing abnormal CD4 + lymphocyte counts with HIV-2 infection was also significantly reduced. This natural history study demonstrates that HIV-2 has a reduced virulence compared to HIV-1.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Nonparametric Estimation from Incomplete Observations
Kaplan, E. L., & Meier, P. (1958) · Journal of the American Statistical Association · doi:10.1080/01621459.1958.10501452 · Cited by 39,158
Cited by
Sousa, A. E., Carneiro, J., Meier-Schellersheim, M., Grossman, Z., & Victorino, R. M. M. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.6.3400 · Cited by 507
Morgan, D., Mahe, C., Mayanja, B., Okongo, J. M., Lubega, R., & Whitworth, J. A. G. (2002) · AIDS · doi:10.1097/00002030-200203080-00011 · Cited by 391
T cell depletion in HIV-1 infection: how CD4+ T cells go out of stock
Hazenberg, M. D., Hamann, D., Schuitemaker, H., & Miedema, F. (2000) · Nature Immunology · doi:10.1038/79724 · Cited by 383
Human immunodeficiency virus type 2
Reeves, J. D., & Doms, R. W. (2002) · Journal of General Virology · doi:10.1099/0022-1317-83-6-1253 · Cited by 369
Lawn, S. D., Butera, S. T., & Folks, T. M. (2001) · Clinical Microbiology Reviews · doi:10.1128/cmr.14.4.753-777.2001 · Cited by 313
Metadata
- Authors
- Marlink, R., Kanki, P., Thior, I., Travers, K., Eisen, G., Siby, T., Traore, I., Hsieh, C.-C., Dia, M. C., Gueye, E.-H., Hellinger, J., Guèye-Ndiaye, A., Sankalé, J.-L., Ndoye, I., Mboup, S., & Essex, M.
- Venue
- Science
- Published
- 1994-09-09
- Volume
- 265
- Issue
- 5178
- Pages
- 1587-1590
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2056360005
- Cited by
- 633
- References
- 1
- FWCI
- 6.67
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Reduced Rate of Disease Development After HIV-2 Infection as Compared to HIV-1. https://app.cochat.ai/papers/10.1126/science.7915856
- The paper
- Marlink, R., Kanki, P., Thior, I., Travers, K., Eisen, G., Siby, T., Traore, I., Hsieh, C.-C., Dia, M. C., Gueye, E.-H., Hellinger, J., Guèye-Ndiaye, A., Sankalé, J.-L., Ndoye, I., Mboup, S., & Essex, M. (1994). Reduced Rate of Disease Development After HIV-2 Infection as Compared to HIV-1. Science. https://doi.org/10.1126/science.7915856
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
